Saavedra-Delgado A M, Metcalfe D D
Ann Allergy. 1985 Nov;55(5):694-702.
This review details the evidence that interactions between food antigens and the immune system may play a role in the pathogenesis of several gastrointestinal diseases. In immediate hypersensitivity reactions to foods involving the gastrointestinal system, in milk-induced gastrointestinal disease in infants and children, and in some forms of hypereosinophilic gastroenteritis, the evidence for the participation of food antigens is extensive. Gluten-induced enteropathy and some forms of dermatitis herpetiformis are also induced by defined food proteins where the response is specific and characteristic. The role of food antigens in the pathogenesis of inflammatory bowel disease is unclear, and warrants further studies.
本综述详细阐述了食物抗原与免疫系统之间的相互作用可能在几种胃肠道疾病发病机制中发挥作用的证据。在涉及胃肠道系统的食物速发型过敏反应、婴幼儿牛奶诱导的胃肠道疾病以及某些形式的嗜酸性粒细胞增多性胃肠炎中，食物抗原参与其中的证据广泛。麸质诱导的肠病和某些形式的疱疹样皮炎也由特定的食物蛋白诱导，其反应具有特异性和特征性。食物抗原在炎症性肠病发病机制中的作用尚不清楚，值得进一步研究。
