Gondos B
Ann Clin Lab Sci. 1985 Sep-Oct;15(5):363-73.
Understanding of the development of the reproductive organs is essential to the evaluation of abnormalities in sexual differentiation. Recent advances resulting from application of genetic, biochemical, and ultrastructural techniques have helped to clarify the mechanisms regulating gonadal and reproductive tract development. The present review considers the major processes of sexual differentiation, development of the female reproductive system and development of the male reproductive system with emphasis on current understanding of basic regulatory mechanisms involved in normal and abnormal development of the reproductive organs.
了解生殖器官的发育对于评估性分化异常至关重要。应用遗传、生化和超微结构技术所取得的最新进展有助于阐明调节性腺和生殖道发育的机制。本综述探讨了性分化的主要过程、女性生殖系统的发育以及男性生殖系统的发育,重点是对生殖器官正常和异常发育所涉及的基本调节机制的当前理解。