端侧吻合在外周节段性神经缺失重建中的应用：一项实验研究。
End-to-side neurorrhaphy in the reconstruction of peripheral segmental neural loss: an experimental study.
机构信息
Universidade do Estado do Pará - Faculdade de Medicina - Laboratório de Cirurgia Experimental - Belém (PA) - Brazil.
Centro Universitário do Pará - Faculdade de Medicina - Laboratório de Cirurgia Experimental - Belém (PA) - Brazil.
出版信息
Acta Cir Bras. 2024 Jul 22;39:e394024. doi: 10.1590/acb394024. eCollection 2024.
PURPOSE
To evaluate the effects on peripheral neural regeneration of the end-to-side embracing repair technique compared to the autograft repair technique in Wistar rats.
METHODS
Fifteen male Wistar rats were divided into three groups with five animals each: denervated group (GD), autograft group (GA), and embracing group (EG). For the evaluation, the grasping test, electroneuromyography (ENMG), and muscle weight assessment were used.
RESULTS
Muscle weight assessment and ENMG did not show significant neural regeneration at the end of 12 weeks in the DG and GE groups, but only in GA. The grasping test showed an increase in strength between the surgery and the fourth week in all groups, and only the GA maintained this trend until the 12th week.
CONCLUSIONS
The present study indicates that the neural regeneration observed in the end-to-side embracing neurorrhaphy technique, in the repair of segmental neural loss, is inferior to autograft repair in Wistar rats.
目的
评估端侧环抱修复技术与自体移植修复技术对 Wistar 大鼠周围神经再生的影响。
方法
将 15 只雄性 Wistar 大鼠随机分为三组，每组 5 只：去神经组（GD）、自体移植组（GA）和环抱组（EG）。采用握力测试、电神经肌图（ENMG）和肌肉重量评估来进行评估。
结果
肌肉重量评估和 ENMG 显示在 12 周末 DG 和 GE 组没有明显的神经再生，但 GA 组有。握力测试显示所有组在手术后和第 4 周之间力量增加，只有 GA 组一直保持到第 12 周。
结论
本研究表明，在修复节段性神经缺失时，端侧环抱神经吻合术观察到的神经再生不如自体移植修复。
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