Cosmetic Ingredient Review Former Senior Scientific Analyst/Writer.
Expert Panel for Cosmetic Ingredient Safety Member.
Int J Toxicol. 2024 Oct;43(4_suppl):78-107. doi: 10.1177/10915818241259699. Epub 2024 Jul 24.
The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 10 polyol phosphates. Some of the possible functions in cosmetics that are reported for this ingredient group are chelating agents, oral care agents, and skin conditioning agents. The Panel reviewed relevant data relating to the safety of these ingredients under the intended conditions of use in cosmetic formulations, and concluded that Sodium Phytate, Phytic Acid, Phytin, and Trisodium Inositol Triphosphate are safe in cosmetics in the present practices of use and concentration described in the safety assessment. The Panel also concluded that the data are insufficient to determine the safety of the following 6 ingredients as used in cosmetics: Disodium Glucose Phosphate, Manganese Fructose Diphosphate, Sodium Mannose Phosphate, Trisodium Fructose Diphosphate, Xylityl Phosphate, and Zinc Fructose Diphosphate.
专家组对 10 种多元醇磷酸盐的安全性进行了评估。据报道，该成分组在化妆品中可能具有螯合剂、口腔护理剂和皮肤调理剂等功能。专家组审查了与这些成分在化妆品配方中预期使用条件下的安全性相关的数据，并得出结论认为，植酸钠、植酸、肌醇六磷酸和三磷酸肌醇在目前使用的安全性评估中描述的使用方法和浓度下，在化妆品中是安全的。专家组还得出结论，目前尚无足够的数据来确定以下 6 种成分在化妆品中的安全性：葡萄糖酸钠磷酸盐、锰果糖二磷酸盐、甘露糖磷酸钠、果糖三磷酸钠、木糖醇磷酸盐和葡萄糖酸锌二磷酸盐。
