Development and Utilization Key Laboratory of Northeast Plant Materials, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China.
College of Chinese Meteria Medica, Shenyang Pharmaceutical University, 103, Wenhua Road, Shenyang, China.
Chem Biodivers. 2024 Oct;21(10):e202400815. doi: 10.1002/cbdv.202400815. Epub 2024 Sep 11.
Hylomecon japonica (Thunb.) Prantl & Kündig (Papaveraceae) has a rich history of traditional medicinal uses, particularly in the treatment of bruises, rheumatism, and various ailments. Recent studies have identified alkaloids, saponins, terpenes, phenols, flavonoids, and other compounds in the plant, all of which demonstrate significant pharmacological effects such as anti-inflammatory and anti-tumor properties. While currently valued for its use in wetland plant landscapes and as a garden design color enhancer, ongoing research on the chemical composition and pharmacological properties of Hylomecon japonica is uncovering its potential medical applications. This paper provides a comprehensive review of extraction and separation methods, chemical components, and pharmacological activities of these compounds to further explore the medicinal potential of Hylomecon japonica.
延胡索(Thunb.)Prantl 和 Kündig(罂粟科)有着丰富的传统药用历史,特别是在治疗瘀伤、风湿和各种疾病方面。最近的研究已经确定了植物中的生物碱、皂苷、萜类、酚类、类黄酮和其他化合物,所有这些都显示出显著的药理作用,如抗炎和抗肿瘤特性。虽然目前因其在湿地植物景观中的应用以及作为花园设计色彩增强剂而受到重视,但对延胡索化学成分和药理活性的持续研究正在揭示其潜在的医学应用。本文综述了这些化合物的提取分离方法、化学成分和药理活性,以进一步探讨延胡索的药用潜力。