Butcher-Puech M C, Henderson-Smart D J, Holley D, Lacey J L, Edwards D A
Arch Dis Child. 1985 Oct;60(10):953-8. doi: 10.1136/adc.60.10.953.
The incidence, duration, and type of apnoea were determined in 28 preterm infants born at 27 to 34 weeks' gestation, using polygraphic records of abdominal breathing movements and nasal airflow. Of the 1520 episodes of apnoea of 10 or more seconds duration, 1002 (66%) lasted 10 to 14 seconds, 311 (20%) lasted 15 to 20 seconds, and 207 (14%) lasted more than 20 seconds. Overall, 69% were central in type, 20% were mixed, and 11% were purely obstructive. With increasing duration of apnoea, the proportion of episodes of central apnoea decreased (69 to 29%) while that of mixed apnoea increased (20 to 60%). Eight infants had obstructive apnoea of more than 20 seconds duration. When they were compared with the 10 infants of similar gestational age and birthweight who had central or mixed apnoea, they had a higher incidence of intraventricular haemorrhage, hydrocephalus, positive pressure ventilation via an endotracheal tube, and abnormal neurological development during the first year of life.
利用腹部呼吸运动和鼻腔气流的多导记录，对28名孕27至34周出生的早产儿的呼吸暂停发生率、持续时间和类型进行了测定。在1520次持续10秒或更长时间的呼吸暂停发作中，1002次（66%）持续10至14秒，311次（20%）持续15至20秒，207次（14%）持续超过20秒。总体而言，69%为中枢性，20%为混合性，11%为单纯阻塞性。随着呼吸暂停持续时间的增加，中枢性呼吸暂停发作的比例下降（从69%降至29%），而混合性呼吸暂停的比例增加（从20%增至60%）。8名婴儿出现了持续超过20秒的阻塞性呼吸暂停。当将他们与10名胎龄和出生体重相似但患有中枢性或混合性呼吸暂停的婴儿进行比较时，他们在出生后第一年内发生脑室内出血、脑积水、通过气管插管进行正压通气以及神经发育异常的发生率更高。
