Department of Stomatology, Nanfang Hospital, Southern Medical University, 1838 N Guangzhou RD, Guangzhou, 510080, Guangdong, People's Republic of China.
BMC Oral Health. 2024 Jul 25;24(1):840. doi: 10.1186/s12903-024-04613-y.
Non-syndromic tooth agenesis (NSTA) is a type of ectodermal dysplasia (ED) in which patients with non-syndromic oligodontia may only affect teeth. No pathological findings were found in other tissues of the ectodermal. Herein, we report a case of a NSTA patient with severe dental anxiety and poor oral health.
A 5-year-old boy without systemic diseases presented as a patient with oligodontia, extensive caries, and periapical periodontitis. Molecular genetic analysis found a mutation in the Ectodysplasin A (EDA) gene, confirming the diagnosis of NSTA.
Tooth agenesis (TA) is the most common ectodermal developmental abnormality in humans. Non-syndromic oligodontia patients often seek treatment in the department of stomatology. Because of their complex oral conditions, these patients should be provided with a systematic and personalized treatment plan.
非综合征性牙齿缺失（NSTA）是一种外胚层发育不良（ED），其中非综合征性少牙症患者可能仅影响牙齿。在外胚层的其他组织中未发现病理发现。在此，我们报告了一例 NSTA 患者，其患有严重的牙齿焦虑和口腔健康不良。
一名 5 岁男孩无系统疾病，表现为少牙症、广泛龋齿和根尖周炎。分子遗传学分析发现 Ectodysplasin A（EDA）基因突变，确诊为 NSTA。
牙齿缺失（TA）是人类最常见的外胚层发育异常。非综合征性少牙症患者通常在口腔科就诊。由于其复杂的口腔状况，应针对这些患者提供系统和个性化的治疗计划。
