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性别医学与睡眠障碍:从基础科学到临床研究

Gender medicine and sleep disorders: from basic science to clinical research.

作者信息

Perger Elisa, Silvestri Rosalia, Bonanni Enrica, Di Perri Maria Caterina, Fernandes Mariana, Provini Federica, Zoccoli Giovanna, Lombardi Carolina

机构信息

Istituto Auxologico Italiano, IRCCS, Sleep Disorders Center and Department of Cardiovascular, Neural and Metabolic Sciences, San Luca Hospital, Milan, Italy.

Sleep Medicine Center, Neurophysiopathology and Movement Disorders Unit, Department of Clinical and Experimental Medicine, University of Messina, AOU "G. Martino", Messina, Italy.

出版信息

Front Neurol. 2024 Jul 10;15:1392489. doi: 10.3389/fneur.2024.1392489. eCollection 2024.

Abstract

Several pivotal differences in sleep and sleep disorders are recognized between women and men. This is not only due to changes in hormonal balance during women's reproductive life, such as in pregnancy and menopause. Women are more likely to report insomnia and non-specific symptoms of apneas, such as fatigue or mood disturbance, compared to men. Thus, it is important for clinicians and researchers to take sex and gender differences into account when addressing sleep disorders in order to acknowledge the biology unique to women. We present a narrative review that delves into the primary sleep disorders, starting from basic science, to explore the impact of gender differences on sleep and the current status of research on women's sleep health.

摘要

人们认识到,女性和男性在睡眠及睡眠障碍方面存在几个关键差异。这不仅是由于女性在生殖期激素平衡的变化,比如怀孕和更年期时的变化。与男性相比,女性更有可能报告失眠以及呼吸暂停的非特异性症状,如疲劳或情绪紊乱。因此,临床医生和研究人员在处理睡眠障碍时考虑性别差异很重要,以便认识到女性特有的生物学特征。我们进行了一项叙述性综述,从基础科学入手深入探讨主要的睡眠障碍,以探究性别差异对睡眠的影响以及女性睡眠健康的研究现状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6739/11267506/ca8edabc93c0/fneur-15-1392489-g0001.jpg

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