da Costa-Oliveira Claudete, Pereira Michele Lafayette, de Carvalho Nicole Ferrari, Silvério Luiza Aparecida Luna, Jessé Ramos Ygor, Mazzola Priscila Gava
Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas 13083-887, Brazil.
APEPI-Medicinal Cannabis Research and Patient Support Association, Rio de Janeiro 20040-030, Brazil.
Pharmacy (Basel). 2024 Jun 27;12(4):100. doi: 10.3390/pharmacy12040100.
Although preliminary evidence suggests 's efficacy in symptom control for anxiety and depression-psychiatric disorders that significantly impact mental health-much remains to be understood about its effects on the central nervous system (CNS) and how to optimize treatment for these disorders. This study aims to conduct a narrative review to evaluate pharmaceutical care in treating symptoms of anxiety and depression alongside use, focusing on safety and therapeutic efficacy optimization. We seek to conceptualize anxiety and depression disorders, review evidence on use, evaluate the evidence quality, and identify knowledge gaps. Twelve articles were identified, revealing a significant gap in the literature regarding the integration of pharmaceutical care with -based therapies, specifically for anxiety and depression. Despite a growing interest in the relationship between and mental health, current research is insufficient for a comprehensive understanding. The relationship between use and anxiety and depression disorders requires further, more targeted investigations. This study underscores the importance of future research to fill existing gaps, providing informed insights and robust guidelines for the safe and effective use of as part of the treatment for anxiety and depression. It is crucial that pharmaceutical care integrates these therapies responsibly to improve the overall well-being of patients.
尽管初步证据表明[具体物质]在控制焦虑和抑郁（对心理健康有重大影响的精神疾病）症状方面具有疗效，但关于其对中枢神经系统（CNS）的影响以及如何优化这些疾病的治疗，仍有许多有待了解之处。本研究旨在进行一项叙述性综述，以评估在使用[具体物质]的同时进行药物治疗对焦虑和抑郁症状的疗效，重点关注安全性和治疗效果的优化。我们试图对焦虑和抑郁障碍进行概念化，回顾关于[具体物质]使用的证据，评估证据质量，并找出知识空白。共识别出12篇文章，结果显示在将药物治疗与基于[具体物质]的疗法相结合治疗焦虑和抑郁方面，文献中存在显著空白。尽管人们对[具体物质]与心理健康之间的关系越来越感兴趣，但目前的研究仍不足以进行全面了解。[具体物质]的使用与焦虑和抑郁障碍之间的关系需要进一步开展更具针对性的研究。本研究强调了未来研究填补现有空白的重要性，为将[具体物质]安全有效地用作焦虑和抑郁治疗的一部分提供明智的见解和有力的指导方针。药物治疗必须负责任地整合这些疗法，以改善患者的整体健康状况。
