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2017年至2022年关于人类尸体组织用于生物力学研究的伦理声明的全球趋势与见解:一项文献计量分析

Global trends and insights in ethical statements regarding the utilization of human cadaveric tissues for biomechanical research from 2017 to 2022: a bibliometric analysis.

作者信息

Zhou Lenian, Qiao Yi, Cai Qianying, Jin Hanqiang, Lin Junqing, Shen Jie, Zhu Hongyi

机构信息

Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.

Institute of Clinical Research, National Center for Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.

出版信息

Int J Surg. 2025 Jan 1;111(1):1503-1507. doi: 10.1097/JS9.0000000000001986.

DOI:10.1097/JS9.0000000000001986
PMID:39051665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11745705/
Abstract

Human cadaveric tissues are essential for biomechanical research; however, omitting statements regarding the ethical implications remains very common in many recent articles of biomechanics. The authors systematically searched PubMed for research articles published from 2017 to 2022 to identify all relevant studies ( n =1850). Information on the characteristics of the cadaveric specimens and the acquisition of ethical approval was collected. The included articles were categorized as grade A ( n =757), grade B ( n =308), and grade C ( n =785) according to the authors' predetermined criteria. Additionally, the authors analyzed whether the reporting status of ethical approval varied based on publishing year, journals, regions, and research settings. No significant improvement was observed over the study period. Disparities in ethical reporting standards were identified among different regions and journals. This is the first bibliometric analysis that offers an overview of publications in biomechanical research that use human cadaveric samples. It serves as a reference for interested researchers and journal readers to discuss the associated ethical issues.

摘要

人体尸体组织对于生物力学研究至关重要;然而,在许多近期的生物力学文章中,省略有关伦理影响的陈述仍然非常普遍。作者系统地在PubMed上搜索了2017年至2022年发表的研究文章,以识别所有相关研究(n = 1850)。收集了关于尸体标本特征和伦理批准获取情况的信息。根据作者预先设定的标准,纳入的文章分为A类(n = 757)、B类(n = 308)和C类(n = 785)。此外,作者分析了伦理批准的报告情况是否因发表年份、期刊、地区和研究环境而有所不同。在研究期间未观察到显著改善。不同地区和期刊之间存在伦理报告标准的差异。这是首次进行的文献计量分析,概述了使用人体尸体样本的生物力学研究中的出版物。它为感兴趣的研究人员和期刊读者讨论相关伦理问题提供了参考。

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本文引用的文献

1
Standardized statement for the ethical use of human cadaveric tissues in anatomy research papers: Recommendations from Anatomical Journal Editors-in-Chief.关于在解剖学研究论文中使用人尸体组织的伦理规范标准声明:《解剖学杂志》总编辑的建议。
Clin Anat. 2022 May;35(4):526-528. doi: 10.1002/ca.23849. Epub 2022 Mar 11.
2
Biomechanical Studies for Glenoid Based Labral Repairs With Suture Anchors Do Not Use Consistent Testing Methods: A Critical Systematic Review.基于关节盂的盂唇修复的生物力学研究:使用缝合锚钉的修复方法并未采用一致的测试方法:一项关键性系统性综述。
Arthroscopy. 2022 Mar;38(3):1003-1018. doi: 10.1016/j.arthro.2021.08.035. Epub 2021 Sep 8.
3
Where do these cadavers come from?
这些尸体从哪里来?
Clin Anat. 2020 Sep;33(6):872-875. doi: 10.1002/ca.23570. Epub 2020 Feb 5.
4
BODIES R US: Ethical Views on the Commercialization of the Dead in Medical Education and Research.《人体交易:医学教育和研究中对死者商业化的伦理观点》。
Anat Sci Educ. 2019 May;12(3):317-325. doi: 10.1002/ase.1809. Epub 2018 Sep 21.
5
Bodies for Anatomy Education in Medical Schools: An Overview of the Sources of Cadavers Worldwide.用于医学院解剖学教育的尸体:全球尸体来源概述。
Acad Med. 2018 Sep;93(9):1293-1300. doi: 10.1097/ACM.0000000000002227.
6
Current status of cadaver sources in Turkey and a wake-up call for Turkish anatomists.土耳其尸体来源的现状与土耳其解剖学家的警钟
Anat Sci Educ. 2018 Mar;11(2):155-165. doi: 10.1002/ase.1713. Epub 2017 Jun 28.
7
Acknowledging tissue donation: Human cadaveric specimens in musculoskeletal research.认可组织捐赠:肌肉骨骼研究中的人类尸体标本
Clin Anat. 2016 Jan;29(1):65-9. doi: 10.1002/ca.22650. Epub 2015 Nov 19.
8
World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects.《世界医学协会赫尔辛基宣言:涉及人类受试者的医学研究伦理原则》
JAMA. 2013 Nov 27;310(20):2191-4. doi: 10.1001/jama.2013.281053.