多敏过敏性鼻炎患者免疫治疗中变应原提取物的选择。
Selection of allergen extract for immunotherapy in polysensitized allergic rhinitis patients.
机构信息
Otolaryngology & Allergology Research Groups, "Unidad Médico Quirúrgica de Otorrinolaringología (UNIMEQ-ORL)", Bogotá, Colombia.
School of Medicine, Universidad de los Andes, Bogotá, Colombia.
出版信息
Immunotherapy. 2024;16(9):623-634. doi: 10.1080/1750743X.2024.2342225. Epub 2024 Jun 3.
Abstract
To evaluate the criteria used by allergists in selecting an immunotherapy extract (allergen immunotherapy [AIT]-extract) in rhinitis patients with polysensitization. First, a cross-sectional study was carried out by evaluating different factors that influence the medical choice of AIT-extract. Second, a literature review was performed by evaluating the diagnostic performance of atopy tests. A total of 419 patients were included (84 children, 149 adolescents and 186 adults). Anamnesis, atopy tests and exposure to pets were the main factors for choosing the AIT extract. The sensitivity and specificity of atopy tests were high for , (>80%), moderate for pets (60%) and indeterminate for . NCTs could be necessary for AIT-extract selection in polysensitized allergic rhinitis patients.
摘要
评估过敏症专家在选择多敏化鼻炎患者的免疫治疗提取物（过敏原免疫治疗[AIT]-提取物）时使用的标准。首先，通过评估影响 AIT-提取物医学选择的不同因素进行了一项横断面研究。其次，通过评估过敏测试的诊断性能进行了文献回顾。共纳入 419 名患者（84 名儿童，149 名青少年和 186 名成年人）。病史、过敏测试和接触宠物是选择 AIT 提取物的主要因素。过敏测试对（>80%）、宠物（60%）和（不确定）的敏感性和特异性较高。对于多敏化过敏性鼻炎患者，AIT-提取物的选择可能需要 NCTs。
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