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Superficial and Invasive Spread of High-grade Squamous Intraepithelial Lesion and Squamous Cell Carcinoma: A Case Report.

作者信息

Nguyen Dan T, Waring Dale, Wan King M, Loo Christine

机构信息

Department of Anatomical Pathology, Prince of Wales Hospital.

Gynaecological Cancer Centre, Royal Hospital for Women.

出版信息

Int J Gynecol Pathol. 2025 May 1;44(3):265-267. doi: 10.1097/PGP.0000000000001062. Epub 2024 Jul 22.

Abstract

We present a case of extensive spread of high-grade squamous intraepithelial lesion (HSIL)/cervical intraepithelial neoplasia grade 3 (CIN3) with foci of invasive squamous cell carcinoma (SCC) in a premenopausal woman. Superficial spread of CIN3 and cervical SCC to the endometrium and/or fallopian tubes is rare, especially in countries with cervical cancer screening programs. Our case occurred during the COVID-19 pandemic, which may have been a major contributing factor to delayed detection and, consequently extensive spread.

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