Sheidaee Kobra, Abbaskhanian Ali, Kali Ali Mohammadi, Motlagh Fatemeh Rostamian, Kargar-Soleimanbad Saeed
Pediatric Infectious Diseases Research Center, Communicable Diseases Institute, Mazandaran University of medical Sciences, Sari, Iran.
Student Research Committee, Faculty of Medicine, Mazandaran University of medical Sciences, Sari, Iran.
Int J Surg Case Rep. 2024 Sep;122:110071. doi: 10.1016/j.ijscr.2024.110071. Epub 2024 Jul 23.
Idiopathic intracranial hypertension (IIH) is a clinical phenomenon that reflects an increase in intracranial pressure in the brain with normal parenchyma and no signs of ventriculomegaly, malignancy, infection, or any space-occupying lesion. Generally, this disease is associated with symptoms such as headache, transient visual obscurations (unilateral or bilateral darkening of the vision typically seconds), intracranial noise, diplopia, blurring of vision, abducens nerve palsies, and unilateral or bilateral facial nerve paresis (which is a very rare complication of this disease that has been reported in some studies).
An 8-year-old boy with a history of bilateral frontal headache for 2 weeks, right ear pain, vomiting, and intermittent fever, who had received antibiotics and analgesics with improvement of ear pain and continuation of headache, presented to this center. In the initial neurological examinations, bilateral papilledema and right-sided 6th and 7th cranial nerve palsy (peripheral) were observed. After performing LP and CT scan and MRV for the patient, a diagnosis of pseudotumor cerebri was made and he was treated with acetazolamide, prednisolone, and topiramate. He was discharged after 10 days.
Although pseudotumor cerebri is less common in children than adults and obesity and female gender are considered as risk factors for this disease, it is not usually associated with involvement of the 6th and 7th cranial nerves. However, sometimes this disease can occur in children without any risk factors and with less common involvement of the 6th and 7th cranial nerves.
特发性颅内高压(IIH)是一种临床现象,反映脑实质正常且无脑室扩大、恶性肿瘤、感染或任何占位性病变迹象的情况下颅内压升高。一般来说,这种疾病与头痛、短暂性视力模糊(通常持续数秒的单眼或双眼视力变暗)、颅内杂音、复视、视力模糊、展神经麻痹以及单侧或双侧面神经麻痹(这是该疾病一种非常罕见的并发症,在一些研究中有报道)等症状相关。
一名8岁男孩,有双侧额部头痛2周、右耳疼痛、呕吐及间歇性发热病史,曾接受抗生素和镇痛药治疗,耳痛好转但头痛持续,前来本中心就诊。在初始神经系统检查中,观察到双侧视乳头水肿及右侧第6和第7颅神经麻痹(周围性)。对该患者进行腰椎穿刺、CT扫描和磁共振静脉血管造影后,诊断为假性脑瘤,并给予乙酰唑胺、泼尼松龙和托吡酯治疗。10天后出院。
尽管假性脑瘤在儿童中比成人少见,肥胖和女性被认为是该疾病的危险因素,但它通常不伴有第6和第7颅神经受累。然而,有时这种疾病可发生在无任何危险因素的儿童中,且第6和第7颅神经受累较少见。