From the Departments of Neurosurgery (W.I.S.), Cedars-Sinai Medical Center, Los Angeles, California
Imaging (M.M.M.), Cedars-Sinai Medical Center, Los Angeles, California.
AJNR Am J Neuroradiol. 2024 Sep 9;45(9):1385-1387. doi: 10.3174/ajnr.A8338.
We investigated whether idiopathic spinal cord herniation is a congenital or acquired condition and undertook a study to determine the risk of developing iSCH in patients with persistent ventral spinal CSF leaks. De novo formation of iSCH was established among all 6 patients with iSCH who had undergone prior spinal imaging for symptoms unrelated to iSCH. Among 51 patients with persistent ventral spinal CSF leaks, iSCH developed in 2 patients (probability increased from 0% at 5 years to 9.4% at 10 years). This study shows that iSCH is an acquired condition, and early treatment of ventral CSF leaks offers a unique opportunity to prevent neurologic disability.
我们研究了特发性脊髓脊膜膨出是先天性的还是后天获得性的，并进行了一项研究，以确定持续性脊髓腹侧脑脊液漏患者发生 iSCH 的风险。在所有 6 例因 iSCH 以外的症状接受过先前脊髓影像学检查的 iSCH 患者中，均发现了新形成的 iSCH。在 51 例持续性脊髓腹侧脑脊液漏患者中，2 例患者发生了 iSCH（5 年时的概率从 0%增加到 10 年时的 9.4%）。本研究表明，iSCH 是后天获得性疾病，早期治疗脊髓腹侧 CSF 漏为预防神经功能障碍提供了独特的机会。
