Tang Jie, Malshy Kamil, Pareek Gyan
Division of Kidney Diseases and Hypertension Alpert Medical School of Brown University, Providence, RI, USA.
Division of Urology Alpert Medical School of Brown University, Providence, RI, USA.
Case Rep Endocrinol. 2024 Jul 17;2024:1252724. doi: 10.1155/2024/1252724. eCollection 2024.
The higher risk for kidney stone in patients with primary hyperparathyroidism is well-documented; stone risk in patients with normocalcemic primary hyperparathyroidism (NPHPT) remains unclear. We present a case of recurrent calcium kidney stones in a patient with severe idiopathic hypercalciuria and NPHPT. The surgical resection of the parathyroid adenoma failed to reduce kidney stone risk (based on the 24-hr urine study) and kidney stone burden (based on ultrasound). This unique case examines the impact of surgical resection of an ectopic parathyroid adenoma on stone risk in a patient with NPHPT and recurrent calcium kidney stones.
原发性甲状旁腺功能亢进患者患肾结石的风险更高，这一点已有充分记录；而血钙正常的原发性甲状旁腺功能亢进（NPHPT）患者的结石风险仍不明确。我们报告一例患有严重特发性高钙尿症和NPHPT的患者复发性钙结石病例。甲状旁腺腺瘤手术切除未能降低肾结石风险（基于24小时尿液研究）和肾结石负荷（基于超声检查）。这个独特的病例研究了异位甲状旁腺腺瘤手术切除对NPHPT和复发性钙结石患者结石风险的影响。
