Qin Feng, Guo Siquan, Yin Xiuwen, Lu Xiaoyu, Ma Jing
The Changzhou Clinical College of Xuzhou Medical University, Changzhou, Jiangsu, China.
Department of Otorhinolaryngology, Changzhou Third People's Hospital, Changzhou, Jiangsu, China.
Front Neurol. 2024 Jul 11;15:1372736. doi: 10.3389/fneur.2024.1372736. eCollection 2024.
This study aims to assess the potential efficacy of cochlear implantation as a treatment for patients with Waardenburg syndrome (WS) and to guide clinical work by comparing the effect of auditory and speech recovery after cochlear implantation in patients with WS and non-WS.
PubMed, the Cochrane Library, CNKI, and Wanfang Data were sources for retrieving literature on cochlear implantation in WS, and clinical data meeting the inclusion criteria were meta-analyzed using RevMan5.41.
A total of nine articles were included in this study, including 132 patients with WS and 815 patients in the control group. Meta-analysis showed that there are no significant differences in the scores for categories of audit performance (CAP), speech intelligibility rating (SIR), and parents' evaluation of aural/oral performance of children (PEACH) between the WS group and the control group.
Cochlear implantation demonstrates comparable auditory and speech recovery outcomes for WS patients and non-WS patients.
本研究旨在评估人工耳蜗植入治疗瓦登伯革综合征(WS)患者的潜在疗效,并通过比较WS患者和非WS患者人工耳蜗植入后听觉和言语恢复效果,为临床工作提供指导。
以PubMed、Cochrane图书馆、中国知网和万方数据为检索来源,检索关于WS患者人工耳蜗植入的文献,并使用RevMan5.41对符合纳入标准的临床资料进行荟萃分析。
本研究共纳入9篇文章,其中WS患者132例,对照组815例。荟萃分析显示,WS组与对照组在听觉表现类别(CAP)评分、言语可懂度评级(SIR)以及儿童听觉/言语表现的家长评估(PEACH)方面无显著差异。
人工耳蜗植入对WS患者和非WS患者的听觉和言语恢复效果相当。