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一名接受女性转男性性别肯定治疗患者新发肺栓塞的诊治:病例报告

Navigation of a New-Onset Pulmonary Embolism in a Patient Receiving Female-to-Male Gender-Affirming Care: A Case Report.

作者信息

Thor Danielle C, Patel Krut, Singh Monisha

机构信息

Internal Medicine, Jefferson Health New Jersey, Stratford, USA.

出版信息

Cureus. 2024 Jun 25;16(6):e63101. doi: 10.7759/cureus.63101. eCollection 2024 Jun.

DOI:10.7759/cureus.63101
PMID:39055476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11270810/
Abstract

The growth of the transgender and/or gender diverse (TGD) community has created an increased demand for comprehensive and evidence-based gender-affirming care, especially when providing a hormone-based regimen. Although there are known risks of adverse events from receiving exogenous hormone replacement therapy, many of these risks are typically attributed to members of the TGD community receiving estrogen-based therapy. In this report, a case of a subsegmental pulmonary embolism in a male patient assigned female at birth who was actively receiving testosterone-based, female-to-male gender-affirming care is detailed. In doing so, attention is drawn to a potential complication of this approach, thereby empowering clinicians and patients alike to be cognizant of such risks while still pursuing this otherwise pivotal and necessary care.

摘要

跨性别和/或性别多元(TGD)群体的壮大,使得对全面且基于证据的性别肯定治疗的需求不断增加,尤其是在提供基于激素的治疗方案时。尽管接受外源性激素替代疗法存在已知的不良事件风险,但其中许多风险通常被认为是接受雌激素治疗的TGD群体成员所面临的。在本报告中,详细介绍了一名出生时被指定为女性的男性患者在积极接受基于睾酮的女变男性别肯定治疗过程中发生亚段肺栓塞的病例。通过这样做,人们注意到了这种治疗方法的一种潜在并发症,从而使临床医生和患者都能在继续寻求这种关键且必要的治疗的同时,意识到此类风险。

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本文引用的文献

1
Caring for Transgender and Gender-Diverse People: Guidelines From WPATH.关爱跨性别者和性别多样化人群:世界跨性别健康专业协会指南
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2
The Impact of Gender Affirming Medical Care During Adolescence on Adult Health Outcomes Among Transgender and Gender Diverse Individuals in the United States: The Role of State-Level Policy Stigma.美国青春期性别肯定医疗对跨性别和性别多样化个体成人健康结果的影响:州级政策污名的作用。
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Assessing and Addressing the Risk of Venous Thromboembolism Across the Spectrum of Gender Affirming Care: A Review.
评估和应对跨性别肯定护理谱中的静脉血栓栓塞风险:综述。
Endocr Pract. 2023 Apr;29(4):272-278. doi: 10.1016/j.eprac.2022.12.008. Epub 2022 Dec 17.
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Risk for Venous Thromboembolism in Transgender Patients Undergoing Cross-Sex Hormone Treatment: A Systematic Review.跨性别患者在接受跨性别激素治疗时发生静脉血栓栓塞的风险:系统评价。
J Sex Med. 2021 Jul;18(7):1280-1291. doi: 10.1016/j.jsxm.2021.04.006. Epub 2021 Jun 16.
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Managing the risk of venous thromboembolism in transgender adults undergoing hormone therapy.管理接受激素治疗的成年跨性别者静脉血栓栓塞的风险。
J Blood Med. 2019 Jul 10;10:209-216. doi: 10.2147/JBM.S166780. eCollection 2019.
9
Ensuring Comprehensive Care and Support for Transgender and Gender-Diverse Children and Adolescents.保障跨性别和性别多样化儿童及青少年的全面关怀和支持。
Pediatrics. 2018 Oct;142(4). doi: 10.1542/peds.2018-2162. Epub 2018 Sep 17.
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