Ożga Joanna, Mężyk Elżbieta, Kmiecik Wojciech, Wojciechowski Wadim, Żuber Zbigniew
Department of Pediatrics, Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Krakow University, Poland.
Clinical Department of Pediatrics and Rheumatology, St. Louis Regional Specialised Children's Hospital, Krakow, Poland.
Reumatologia. 2024;62(3):196-206. doi: 10.5114/reum/190262. Epub 2024 Jul 12.
Magnetic resonance imaging (MRI) of the musculoskeletal system is an examination increasingly performed for suspected juvenile idiopathic arthritis, chronic nonbacterial osteomyelitis and juvenile idiopathic inflammatory myopathies, as well as other rheumatic diseases of developmental age. T1-, T2- and PD-weighted with or without fat suppression or short tau inversion recovery/turbo inversion recovery magnitude (STIR/TIRM) sequences and post-contrast sequences are evaluated to diagnose pathological changes in the synovial membrane, subchondral bone marrow and surrounding soft tissues. Magnetic resonance imaging allows detection of synovitis, tenosynovitis, bursitis, and enthesitis as well as bone marrow edema and soft tissue edema. Several pediatric-specific MRI scoring systems have been developed and validated to standardize and facilitate the assessment of the extent of the inflammatory process and disease activity in MRI. Early detection of inflammatory changes allows the inclusion of comprehensive pharmacotherapy giving the possibility of permanent remission and objective measurement of the effectiveness of treatment.
肌肉骨骼系统的磁共振成像(MRI)检查越来越多地用于疑似幼年特发性关节炎、慢性非细菌性骨髓炎和幼年特发性炎性肌病以及其他发育年龄的风湿性疾病。对有或没有脂肪抑制的T1加权、T2加权和质子密度加权序列或短tau反转恢复/快速反转恢复幅度(STIR/TIRM)序列以及增强后序列进行评估,以诊断滑膜、软骨下骨髓和周围软组织的病理变化。磁共振成像能够检测滑膜炎、腱鞘炎、滑囊炎和附着点炎以及骨髓水肿和软组织水肿。已经开发并验证了几种针对儿科的MRI评分系统,以标准化并促进对MRI中炎症过程的程度和疾病活动的评估。炎症变化的早期检测有助于采用综合药物治疗,从而有可能实现永久缓解并客观测量治疗效果。