Smith U
Int J Obes. 1985;9 Suppl 1:145-8.
Recent studies have shown that adipose tissue metabolism varies in different regions. Thus, hormonal responsiveness and sensitivity to both lipolytic and anti-lipolytic agent is increased in abdominal as compared to femoral cells. Abdominal obesity is also associated with greater aberrations in metabolism than peripheral obesity. The increased lipolytic response in abdominal fat cells may lead to higher FFA concentrations, which may attenuate both glucose uptake and insulin clearance by the liver.
最近的研究表明，不同区域的脂肪组织代谢存在差异。因此，与股部细胞相比，腹部细胞对激素的反应性以及对脂解剂和抗脂解剂的敏感性均有所增强。与外周型肥胖相比，腹部肥胖在代谢方面也存在更大的异常。腹部脂肪细胞中脂解反应的增强可能导致游离脂肪酸（FFA）浓度升高，这可能会削弱肝脏对葡萄糖的摄取及胰岛素清除能力。
