Keller J, Simon M, Fartasch M, Hornstein O P
Hautarzt. 1985 Sep;36(9):512-5.
A 49-year-old patient with concomitant solar urticaria (SU) and lichen planus (LP) is presented. The sunlight- and UV-A-provoked wheal and flare SU reactions were interpreted as an antigen-antibody reaction, probably involving a reaginic antibody, because SU was passively transferred by a serum factor utilizing the Prausnitz-Küstner reaction. The reduced percentage of suppressor cytotoxic T-cell subset in peripheral blood typical of active LP may facilitate the increased production of reaginic antibodies after presentation of antigen by sunlight. Not only was the usual immunological reaction of LP (similar to graft-versus-host reaction) suppressed by PUVA treatment, but increased tolerance to sunlight was also achieved.
本文报告了一名49岁同时患有日光性荨麻疹(SU)和扁平苔藓(LP)的患者。日光和紫外线A引发的风团及潮红SU反应被解释为抗原抗体反应,可能涉及反应素抗体,因为利用普劳斯尼茨-屈斯特纳反应,SU可通过血清因子被动转移。活动性LP典型的外周血中抑制性细胞毒性T细胞亚群百分比降低,可能促使在抗原经日光呈递后反应素抗体产生增加。不仅PUVA治疗抑制了LP常见的免疫反应(类似于移植物抗宿主反应),还实现了对日光耐受性的提高。