Unveiling the Moderating Factors in the Relationship between Physical Activity and Health-Related Quality of Life among University Students during COVID-19: A Mixed Study Design.

This study examines the moderating effects of various factors on the relationship between physical activity (PA) and health-related quality of life (HRQoL) among 287 female college students during the COVID-19 pandemic. Data were collected through an online questionnaire covering health issues, PA, self-esteem, HRQoL, and sociodemographic information, supplemented by semi-structured interviews and focus groups with six participants. Results showed that 46% of respondents had good HRQoL, and 38% were physically active. The interactions of age, socioeconomic status (SES), and academic performance with PA on HRQoL were insignificant. However, physical and mental health problems significantly moderated the PA-HRQoL relationship, accounting for 1% and 4% of the variance, respectively. The qualitative analysis highlighted the need for student activity clubs and mental health support to enhance coping strategies and overall HRQoL. In conclusion, age and SES did not moderate the PA-HRQoL relationship, while physical and mental health issues did. Programs targeting students with health problems are crucial to improving their physical and mental health, thereby enhancing their well-being.