Dickinson John W, Smyth Carol M E, Winter Samantha L
School of Sport and Exercise Sciences, University of Kent, Canterbury, Kent, UK.
School of Sport, Exercise and Health Sciences, Loughborough University, National Centre for Sport and Exercise Medicine, Loughborough, UK.
J Asthma. 2025 Jan;62(1):14-23. doi: 10.1080/02770903.2024.2383632. Epub 2024 Jul 26.
To determine whether Opto-Electronic Plethysmography (OEP) can distinguish Exercise-Induced Bronchoconstriction (EIB) breathing patterns by comparing individuals with and without EIB, and between broncho-constriction and recovery. Breathing pattern was quantified in terms of regional contribution, breathing timing, and the phase between chest sub-compartments which indicates the synchronization in movement of the different sub-compartments.
Individuals ( = 47) reporting no respiratory symptoms and no history of any respiratory disease or disorder were assumed to have a healthy breathing pattern. Of 38 participants reporting respiratory symptoms during exercise, and/or a previous diagnosis of asthma or EIB, 10 participants had a positive result to the Eucapnic Voluntary Hyperpnea test, defined as a fall of at least 10% in FEV from baseline at two consecutive time points and were classified into the EIB group. OEP data was obtained from 89 markers and an 11-camera motion capture system operating at 100 Hz as follows: pre- and post-EVH challenge, and post-inhaler in participants who experienced a bronchoconstriction, and 2) for the healthy group during tidal breathing.
RCpRCa-Phase (upper versus lower ribcage), RCaS-Phase (lower ribcage versus shoulders), and RCpS-Phase (upper ribcage versus shoulders) differed between bronchoconstriction and rest in athletes with EIB and rest in healthy participants ( < 0.05), in all cases indicating greater asynchrony post-bronchoconstriction, and later movement of the abdominal ribcage (RCa) post-bronchoconstriction. RCpS-Phase was different ( < 0.05) between all conditions (rest, post-bronchoconstriction, and post-inhaler) in EIB.
OEP can characterize and distinguish EIB-associated breathing patterns compared to rest and individuals without EIB at rest.
通过比较有和没有运动诱发支气管收缩（EIB）的个体，以及支气管收缩和恢复之间的情况，来确定光电体积描记法（OEP）是否能够区分EIB的呼吸模式。呼吸模式通过区域贡献、呼吸时间以及胸部子区域之间的相位进行量化，该相位表明了不同子区域运动的同步性。
报告无呼吸道症状且无任何呼吸道疾病或紊乱病史的个体（n = 47）被假定具有健康的呼吸模式。在38名报告运动期间有呼吸道症状和/或既往有哮喘或EIB诊断的参与者中，10名参与者在等二氧化碳过度通气试验中结果为阳性，定义为在两个连续时间点FEV较基线下降至少10%，并被分类为EIB组。OEP数据从89个标记和一个以100 Hz运行的11相机动作捕捉系统中获取，如下所示：1）在经历支气管收缩的参与者中，进行等二氧化碳过度通气（EVH）激发前后以及吸入器使用后；2）在健康组进行潮气呼吸期间。
EIB运动员在支气管收缩时与休息时以及健康参与者休息时相比，肋笼上-肋笼下相位（RCpRCa-Phase）、肋笼下-肩部相位（RCaS-Phase）和肋笼上-肩部相位（RCpS-Phase）存在差异（P < 0.05），在所有情况下均表明支气管收缩后不同步性增加，且支气管收缩后腹部肋笼（RCa）运动延迟。EIB组在所有状态（休息、支气管收缩后和吸入器使用后）之间，RCpS-Phase存在差异（P < 0.05）。
与休息时以及休息时没有EIB的个体相比，OEP能够表征和区分与EIB相关的呼吸模式。
