通过 CCAR1 对 DNA 修复进行剪接调控。
Splicing regulation of DNA repair via CCAR1.
机构信息
Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
出版信息
Mol Cell. 2024 Jul 25;84(14):2591-2592. doi: 10.1016/j.molcel.2024.06.012.
PMID:39059366
Abstract
In this issue of Molecular Cell, Harada et al. and Karasu et al. identify CCAR1 as a novel regulator of the Fanconi anemia/BRCA DNA repair pathway via modulating the splicing of the mRNA encoding FANCA.
摘要
在本期《分子细胞》中，Harada 等人和 Karasu 等人发现 CCAR1 可通过调节编码 FANCA 的 mRNA 的剪接，作为一种新型的范可尼贫血/BRCA 修复途径的调控因子。
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