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新冠疫情后时期的新医务人员导致抗生素治疗质量发生改变。

New medical staff in the post-COVID-19 period entailed altered quality of antibiotic therapy.

机构信息

Infectiologie, Polyclinique Les Fleurs, Ave Frédéric Mistral, Ollioules, France; Cellule Recherche et Enseignement, Groupe Elsan, Territoire Provence Alpes-Côte d'Azur, France.

Hygiène Hospitalière, Médipôle St Roch, rue Ambroise Croizat, 66330 Cabestany, France.

出版信息

Infect Dis Now. 2024 Sep;54(6):104957. doi: 10.1016/j.idnow.2024.104957. Epub 2024 Jul 24.

DOI:10.1016/j.idnow.2024.104957
PMID:39059497
Abstract

OBJECTIVE

Our aim was to audit antibiotic prescriptions from renewed medical staff.

METHODS

A retrospective multicenter audit of antibiotic therapies was performed in four institutions with similar antimicrobial stewardship programs. We compared antibiotic prescriptions from physicians practicing before and after the pandemic. Antibiotic prescriptions were classified as optimal (OAT), suboptimal (SAT) or unnecessary antibiotic therapy (UAT).

RESULTS

All in all, 165 antibiotic courses was audited in 2023: OAT, SAT and UAT rates were 21, 42 and 38% respectively. Sixty-seven out of 165 (41%) prescriptions were given by new physicians. In multivariate analysis, antibiotic prescriptions from the latter compared to former were associated with less diagnosis of infection written in patient charts: AOR [CI 95%] 3.68 [1.53-8.83], and with UAT: 2.76 [1.34-5.68].

CONCLUSIONS

Ensuring adequate antibiotic prescriptions with renewed medical staff requires a high level of education and training.

摘要

目的

我们旨在审核新入职医务人员开具的抗生素处方。

方法

在四家具有相似抗菌药物管理计划的机构中,进行了抗生素治疗的回顾性多中心审核。我们比较了大流行前后执业医生开具的抗生素处方。抗生素处方分为优化(OAT)、次优(SAT)或不必要的抗生素治疗(UAT)。

结果

共审核了 2023 年 165 例抗生素疗程:OAT、SAT 和 UAT 的比例分别为 21%、42%和 38%。165 例处方中有 67 例(41%)由新医生开具。多变量分析显示,与前者相比,后者开具的抗生素处方与患者病历中感染诊断较少有关:比值比 [95%CI] 3.68 [1.53-8.83],以及不必要的抗生素治疗:2.76 [1.34-5.68]。

结论

确保新入职医务人员开具适当的抗生素处方需要进行高水平的教育和培训。

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Infect Dis Now. 2024 Sep;54(6):104957. doi: 10.1016/j.idnow.2024.104957. Epub 2024 Jul 24.
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