Vácha J
J Med Philos. 1985 Nov;10(4):339-67. doi: 10.1093/jmp/10.4.339.
From the end of the First World War, a broad discussion took place within the framework of the revived German constitutional teaching on the question of the physical normality of man. The founder of the so-called statistical concept of normality, which preceded the still widespread normal (reference) interval concept, is H. Rautmann, who gave it the character of a tool for discriminating between health and disease. Among some of his successors (Bauer, Borchardt, Günther), however, it was considered more a means of establishing a type, without supposing any precise relation between the frequency of a character in the population and the probability of the occurrence of disease. The concept of a statistical norm as a certain region of the variation range of a character determined by the parameters of Gaussian distribution was criticized both by the supporters of the ideal norm (Hildebrandt) and those who were in favour of a 'personal' norm (Grote). The underlying motifs of these three conceptions of normality influenced German constitutional doctrine until after the end of the Second World War, but without a satisfactory solution to the diagnosis of physical normality being found. Since the 1950s, world medicine has moved more and more in the direction of prevention, with the emphasis on a study of individual dispositions to disease and its precursors. In this connection a new view of health has gained importance whereby it is considered a smoothly gradated condition, not sharply distinguished from disease ('continual' model of health and disease as opposed to the previous 'alternative' model). The purpose of diagnostic characters is no longer merely to place patients in clearly defined categories as healthy or affected by one disease or another, but has taken on the function of indices of the disposition to disease among those who exhibit 'gross normality'. Discrimination between the alternative and continuous models allows a clarification to be made of the sources of the confusion in which the pre-war concept of statistical normality had found itself. Today many exceptions are known to the rule that the functional optimum lies in the region of the population mean, both for the population as a whole and for individuals; and immense variability has been found in the manner in which individuals in the population attain health.(ABSTRACT TRUNCATED AT 400 WORDS)
从第一次世界大战结束起,在复兴的德国宪法学说框架内,就人类身体正常性问题展开了广泛讨论。所谓常态统计概念的创始人是H. 劳特曼,该概念先于如今仍广泛使用的正常(参考)区间概念,他赋予其作为区分健康与疾病工具的特性。然而,在他的一些继任者(鲍尔、博夏特、京特)看来,它更多是确立一种类型的手段,并未假定人群中某种特征的频率与疾病发生概率之间存在任何精确关系。作为由高斯分布参数确定的某种特征变异范围特定区域的统计常态概念,受到了理想常态支持者(希尔德布兰特)以及支持“个人”常态者(格罗特)的批评。这三种常态概念的潜在主题一直影响着德国宪法学说,直至第二次世界大战结束后,但始终未能找到关于身体正常性诊断的令人满意的解决方案。自20世纪50年代以来,世界医学越来越朝着预防方向发展,重点是研究个体对疾病及其先兆的易感性。在此背景下,一种新的健康观变得越发重要,即认为健康是一种渐变状态,与疾病并无明显区分(健康与疾病的“连续”模型,与之前的“替代”模型相对)。诊断特征的目的不再仅仅是将患者明确归类为健康或患有某种疾病,而是在表现出“总体正常”的人群中承担起疾病易感性指标的功能。区分替代模型和连续模型有助于厘清战前统计常态概念所处的混乱根源。如今,对于功能最优值位于总体均值区域这一规则,无论是对于整个总体还是个体而言,都存在许多例外情况;并且人们发现,总体中的个体实现健康的方式存在巨大差异。(摘要截断于400字)