Andersch B, Hahn L
J Psychosom Res. 1985;29(5):489-93. doi: 10.1016/0022-3999(85)90082-0.
Fifteen women with moderate to severe premenstrual symptoms, defined and graded according to a recently developed scoring system, took part in a double blind study of the effect of progesterone on premenstrual symptoms. The dosage was 100 mg progesterone twice daily delivered in vaginal pessaries. The women were improved with a statistically significant decrease in their scores by progesterone as well as by placebo treatment. There was no statistically significant difference between the two regimes.
根据最近制定的评分系统定义和分级，15名有中度至重度经前症状的女性参与了一项关于孕酮对经前症状影响的双盲研究。剂量为每天两次，每次100毫克孕酮，通过阴道栓剂给药。孕酮和安慰剂治疗均使这些女性的症状有所改善，评分有统计学意义的下降。两种治疗方案之间没有统计学上的显著差异。
