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内科外周静脉治疗——两年观察研究中抗生素及其他药物的使用情况与血管通路装置特点

Peripheral Intravenous Therapy in Internal Medicine Department-Antibiotics and Other Drugs' Consumption and Characteristics of Vascular Access Devices in 2-Year Observation Study.

作者信息

Piekiełko Piotr, Mucha Anna, Stawowczyk Ewa, Wójkowska-Mach Jadwiga

机构信息

Department of Internal Diseases and Circulatory Failure, Center of Pulmonology and Thoracic Surgery in Bystra, Juliana Fałata 2 Street, 43-360 Bystra, Poland.

Department of Pulmonology and Respiratory Failure, Center of Pulmonology and Thoracic Surgery in Bystra, Juliana Fałata 2 Street, 43-360 Bystra, Poland.

出版信息

Antibiotics (Basel). 2024 Jul 18;13(7):664. doi: 10.3390/antibiotics13070664.

Abstract

BACKGROUND

The aim of the study was to characterize the procedure of peripheral intravenous therapy (IT), including the characteristics of vascular access and related complications and qualitative and quantitative analyses of drug consumption.

MATERIALS AND METHODS

A two-year, retrospective, single-center observational study was conducted. The criterion for including a patient in the study was the use of peripheral intravenous catheters (PIVCs) upon admission or during the stay at the internal medicine department (IMD).

RESULTS

The main reasons for hospitalization were exacerbations of chronic diseases for 78% of the patients and acute infections for 22%. IT was used in 83.6% of all the patients. IT was used primarily for antibiotics (5009.9 defined daily doses (DDD)). Further, 22.6% of the PIVCs stopped functioning within 24 h, more frequently in infectious patients. The main reasons for PIVC removal were leakage (n = 880, 26.6%) and occlusion (n = 578, 17.5%). The PIVC locations were mostly suboptimal (n = 2010, 59.5%), and such locations were related to leakage and occlusion ( = 0.017).

CONCLUSIONS

In the IMD, most patients require the use of a PIVC, and antibiotics dominate the group of drugs administered intravenously. Up to 1/5 of peripheral intravenous catheters are lost within the first 24 h after their insertion, with most of them placed suboptimally. A properly functioning PIVC appears to be crucial for antimicrobial treatment.

摘要

背景

本研究的目的是描述外周静脉治疗(IT)的过程,包括血管通路的特点、相关并发症以及药物消耗的定性和定量分析。

材料与方法

进行了一项为期两年的回顾性单中心观察性研究。纳入本研究的患者标准是入院时或在内科病房(IMD)住院期间使用外周静脉导管(PIVC)。

结果

78%的患者住院的主要原因是慢性病加重,22%是急性感染。所有患者中有83.6%使用了IT。IT主要用于抗生素(5009.9限定日剂量(DDD))。此外,22.6%的PIVC在24小时内失去功能,在感染患者中更常见。拔除PIVC的主要原因是渗漏(n = 880,26.6%)和堵塞(n = 578,17.5%)。PIVC的位置大多不理想(n = 2010,59.5%),且这些位置与渗漏和堵塞有关(P = 0.017)。

结论

在内科病房,大多数患者需要使用PIVC,抗生素在静脉给药药物组中占主导地位。高达1/5的外周静脉导管在插入后的头24小时内失去功能,其中大多数位置不理想。功能正常的PIVC似乎对抗菌治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c400/11274068/9649b1993cd5/antibiotics-13-00664-g001.jpg

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