Zhang Dongyan, Li Jing, Zhang Bo, Shao Yuxin, Wang Zheng
Institute of Animal Science and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China.
Animals (Basel). 2024 Jul 17;14(14):2087. doi: 10.3390/ani14142087.
We aimed to explore the effects of two different doses of Zn on the fecal microbiota in pigeons and the correlation between these effects and intestinal immune status. Zn doses affected pigeon growth performance, and pigeons in the T60 (60 mg/kg Zn) and T90 (90 mg/kg Zn) groups exhibited higher villus height and crypt depth in duodenum and ileum compared to the control group, respectively. Supplementation with Zn increased the expression of the , , and genes ( < 0.05), while enhancing serum immunoglobulin (Ig) G, IgM, and IgA concentrations compared to the control pigeons ( < 0.05). T60 treatment reduced relative Actinobacteriota abundance, while spp. abundance was highest in the T90 group compared to the two other groups. The core functional genera significantly associated with immune indices in these pigeons were and . Our findings will help facilitate the application of dietary Zn intake in pig production.
我们旨在探讨两种不同剂量的锌对鸽子粪便微生物群的影响，以及这些影响与肠道免疫状态之间的相关性。锌剂量影响鸽子的生长性能，与对照组相比，T60（60 mg/kg锌）和T90（90 mg/kg锌）组的鸽子十二指肠和回肠绒毛高度和隐窝深度分别更高。与对照鸽子相比，补充锌增加了 、 、 和 基因的表达（ < 0.05），同时提高了血清免疫球蛋白（Ig）G、IgM和IgA浓度（ < 0.05）。T60处理降低了放线菌门相对丰度，而与其他两组相比，T90组中 属丰度最高。这些鸽子中与免疫指标显著相关的核心功能属为 和 。我们的研究结果将有助于促进日粮锌摄入量在养猪生产中的应用。
