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具有综合征演变的单对称头胸联体四臂四足仔猪

Monosymmetros Cephalothoracopagus Tetrabrachius and Tetrapus Piglets with Syndromic Evolution.

作者信息

Marc Simona, Crăciun Ioan Claudiu, Sicoe Bogdan, Savici Jelena, Boldura Oana Maria, Paul Cristina, Otavă Gabriel, Văduva Cristina, Stancu Adrian

机构信息

Faculty of Veterinary Medicine, University of Life Sciences "King Mihai I" from Timișoara, Calea Aradului 119, 300645 Timișoara, Romania.

Department of Applied Chemistry and Engineering of Organic and Natural Compounds, Faculty of Industrial Chemistry and Environmental Engineering, Politehnica University Timișoara, Vasile Pârvan 6, 300223 Timișoara, Romania.

出版信息

Animals (Basel). 2024 Jul 21;14(14):2127. doi: 10.3390/ani14142127.

Abstract

Conjoined twins are rare congenital malformations that have been reported in mammals. Two different cases are presented in this study. Case No. 1 features monocephalic, thoracopagus-conjoined twin piglets with anencephaly and palatoschisis of the Pietrain breed, and case No. 2 features monocephalic, thoracopagus conjoined twin piglets with palatoschisis and bifid root tongue of a mixed breed. These cases were examined using post-mortem and computed tomography (CT) examinations. In both cases, the conjoined symmetrical twins had a single head, one neck, and fused thoracic cavities, while the abdominal cavities were separated. Similarly, in both cases, they had four forelimbs and four hindlimbs and duplicated foramen magnum. During CT examination, in case No. 1, severe abnormalities were observed in the skull and vertebral column. In the left twin, occult dysraphism was seen from the C2 vertebra until the end of the vertebral column, and in the right twin, from the C3 vertebra until the end of the state vertebral level. In case No. 2, the oral cavity contained a tongue with a bifid root connected with one hyoid bone, and the soft palate presented a small cleft. During CT examination, the parietal bone and the occipital bones were partially duplicated. This case also presented occult dysraphism, but only in the cervical vertebrae, C1-C6 for the left twin and C1-C5 for the right twin. In both cases, abnormalities of the internal organs were revealed during necropsy. Conjoined twins with multiple congenital anomalies presented here enhance our understanding of the various clinical forms of conjoined cases in veterinary medicine.

摘要

联体双胎是一种在哺乳动物中报道过的罕见先天性畸形。本研究呈现了两例不同的病例。病例1为皮特兰品种的单头、胸部联体双胎仔猪,伴有无脑畸形和腭裂;病例2为混种的单头、胸部联体双胎仔猪,伴有腭裂和双叉舌根。对这些病例进行了尸检和计算机断层扫描(CT)检查。在这两个病例中,联体对称双胎均有一个头、一个颈部和融合的胸腔,而腹腔是分开的。同样,在这两个病例中,它们都有四条前肢和四条后肢以及两个枕骨大孔。在CT检查中,病例1在颅骨和脊柱中观察到严重异常。在左侧双胎中,从第2颈椎直到脊柱末端可见隐性脊柱裂,在右侧双胎中,从第3颈椎直到该状态脊柱水平末端可见隐性脊柱裂。在病例2中,口腔内有一条双叉舌根的舌头与一块舌骨相连,软腭有一个小裂隙。在CT检查中,顶骨和枕骨部分重复。该病例也存在隐性脊柱裂,但仅在颈椎,左侧双胎为C1 - C6,右侧双胎为C1 - C5。在这两个病例中,尸检时均发现了内脏器官异常。这里呈现的具有多种先天性异常的联体双胎增强了我们对兽医学中联体病例各种临床形式的理解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c28b/11274208/f30b9826b0cd/animals-14-02127-g001.jpg

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