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传染性单核细胞增多症继发自发性脾破裂

Spontaneous Splenic Rupture Secondary to Infectious Mononucleosis.

作者信息

Kountouri Ismini, Vitkos Evangelos N, Dimasis Periklis, Chandolias Miltiadis, Galani Manolakou Maria Martha, Gkiatas Nikolaos, Manolakaki Dimitra

机构信息

Department of General Surgery, General Hospital of Katerini, 60100 Katerini, Greece.

出版信息

Diagnostics (Basel). 2024 Jul 16;14(14):1536. doi: 10.3390/diagnostics14141536.

DOI:10.3390/diagnostics14141536
PMID:39061673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11275484/
Abstract

Spontaneous splenic rupture (SSR) is a relatively rare but potentially lethal complication of infectious mononucleosis (IM). While SSR is extremely rare in patients with proven IM, it is the most lethal complication of the infection (9% mortality rate) and can present completely asymptomatically or with abdominal pain and hemodynamic instability. As adolescents and young adults are the most affected population group, with this case report, we intend to raise the vigilance of any doctor treating those patients in the emergency department. We present the case of a 16-year-old patient with an atraumatic splenic rupture and hemoperitoneum secondary to an Epstein-Barr virus (EBV) infection. The patient underwent an exploratory laparotomy, and a splenectomy was performed. This case demonstrates that, even if SSR in patients with IM is extremely rare, it should always be considered in a patient with a relevant clinical presentation.

摘要

自发性脾破裂(SSR)是传染性单核细胞增多症(IM)相对罕见但可能致命的并发症。虽然在确诊为IM的患者中SSR极为罕见,但它是该感染最致命的并发症(死亡率为9%),可完全无症状出现,或伴有腹痛和血流动力学不稳定。由于青少年和青年是受影响最严重的人群,通过本病例报告,我们旨在提高急诊科任何治疗这些患者的医生的警惕性。我们报告一例16岁患者,因感染爱泼斯坦-巴尔病毒(EBV)继发非创伤性脾破裂和腹腔积血。该患者接受了剖腹探查术,并进行了脾切除术。本病例表明,即使IM患者中的SSR极为罕见,但对于有相关临床表现的患者,始终应考虑到这种情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/504f/11275484/4950b5370cbe/diagnostics-14-01536-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/504f/11275484/3f1146890ae7/diagnostics-14-01536-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/504f/11275484/4950b5370cbe/diagnostics-14-01536-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/504f/11275484/3f1146890ae7/diagnostics-14-01536-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/504f/11275484/4950b5370cbe/diagnostics-14-01536-g002.jpg

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本文引用的文献

1
EBV : not your Everyday Benign Virus.爱泼斯坦-巴尔病毒:并非普通的良性病毒。
Acta Gastroenterol Belg. 2020 Jul-Sep;83(3):485-487.
2
Spontaneous splenic rupture in a patient with infectious mononucleosis.传染性单核细胞增多症患者自发性脾破裂。
BMJ Case Rep. 2019 Sep 30;12(9):e230259. doi: 10.1136/bcr-2019-230259.
3
Infectious Mononucleosis Management in Athletes.运动员传染性单核细胞增多症的管理。
Clin Sports Med. 2019 Oct;38(4):555-561. doi: 10.1016/j.csm.2019.06.002. Epub 2019 Jul 29.
4
Adolescent With Spontaneous Splenic Rupture as a Cause of Hemoperitoneum in the Emergency Department: Case Report and Literature Review.青少年自发性脾破裂致急诊腹腔积血 1 例报告并文献复习
Pediatr Emerg Care. 2020 Dec;36(12):e737-e741. doi: 10.1097/PEC.0000000000001520.
5
Atraumatic splenic rupture secondary to Epstein-Barr virus infection.爱泼斯坦-巴尔病毒感染继发的非创伤性脾破裂
BMJ Case Rep. 2017 Jan 24;2017:bcr2016218405. doi: 10.1136/bcr-2016-218405.
6
Epstein-Barr Virus-Associated Atraumatic Spleen Laceration Presenting with Neck and Shoulder Pain.表现为颈部和肩部疼痛的爱泼斯坦-巴尔病毒相关非创伤性脾破裂
Am J Case Rep. 2015 Oct 30;16:774-7. doi: 10.12659/ajcr.893919.
7
Spontaneous splenic rupture: A rare life-threatening condition; Diagnosed early and managed successfully.自发性脾破裂:一种罕见的危及生命的病症;早期诊断并成功治疗。
Am J Case Rep. 2013;14:13-5. doi: 10.12659/AJCR.883739. Epub 2013 Jan 15.
8
Splenic rupture and infectious mononucleosis-splenectomy, splenorrhaphy or non operative management?脾破裂与传染性单核细胞增多症——脾切除术、脾修补术还是非手术治疗?
J R Soc Med. 1992 Aug;85(8):458-9. doi: 10.1177/014107689208500812.