Department of Radiology, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 400347 Iasi, Romania.
Department of Morpho-Functional Sciences I, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 400347 Iasi, Romania.
Biomolecules. 2024 Jun 30;14(7):784. doi: 10.3390/biom14070784.
With the rise in longevity within the population, medicine continues to encounter fresh hurdles necessitating prompt actions, among which are those associated with hip joint aging. Age-related arthropathies encompass damage to bones' articulating extremities and their supporting structures, such as articular cartilage, and alterations in the quantity and quality of synovial fluid. This study aims to summarize the biomolecular methods of hip joint evaluation focused on its vascularization, using data correlated with biomolecular research on other joints and tissues, in order to reach an objective opinion of the study prospects in this field. Following a retrospective study on most modern biomolecular research methods on the synovium, the capsule, and the articular cartilage of the hip joint, we have hereby concretized certain future research directions in this field that will improve the qualitative and morphofunctional management of the hip joint at an advanced age, even within population categories at risk of developing various degenerative joint pathologies.
随着人口寿命的延长，医学继续面临新的挑战，需要迅速采取行动，其中包括与髋关节老化相关的挑战。与年龄相关的关节病包括骨骼关节末端及其支持结构（如关节软骨）的损伤，以及滑液数量和质量的变化。本研究旨在总结髋关节评估的生物分子方法，重点关注其血管化，使用与其他关节和组织的生物分子研究相关的数据，以对该领域的研究前景形成客观的看法。在对髋关节滑膜、囊和关节软骨的大多数现代生物分子研究方法进行回顾性研究后，我们在此确定了该领域的一些未来研究方向，这些方向将改善高龄人群髋关节的定性和形态功能管理，甚至可以改善有各种退行性关节病变风险的人群的髋关节管理。
