Fredrickson P, Richelson E
J Clin Psychiatry. 1979 Sep;40(9):399-405.
Considerable evidence exists linking dopamine with schizophrenia. Other neurotransmitters including acetylcholine, serotonin and gamma-aminobutyric acid (GABA) are also being implicated. Neurotransmitters act via receptors on brain cells and evidence suggests that antipsychotic drugs exert their therapeutic actions and produce side effects by receptor blockade.
有大量证据表明多巴胺与精神分裂症有关。包括乙酰胆碱、血清素和γ-氨基丁酸(GABA)在内的其他神经递质也被牵涉其中。神经递质通过脑细胞上的受体起作用,并且有证据表明抗精神病药物通过受体阻断发挥其治疗作用并产生副作用。