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心脏手术后既往有卒中史患者的结局评估:一项单中心研究。

Evaluation of Outcomes in Patients with Previous Stroke History following Cardiac Surgery: A Single-Center Study.

作者信息

Pacholewicz Jerzy, Walerowicz Paweł, Szylińska Aleksandra, Udzik Jakub, Wańkowicz Paweł, Kuligowska Ewelina, Szuba Ewelina, Listewnik Mariusz

机构信息

Department of Cardiac Surgery, Pomeranian Medical University, 70-111 Szczecin, Poland.

Department of Social Medicine and Public Health, Pomeranian Medical University, 70-103 Szczecin, Poland.

出版信息

J Clin Med. 2024 Jul 10;13(14):4045. doi: 10.3390/jcm13144045.

Abstract

: The aim of the study to analyze the risk of complications, including neurological sequelae, alongside early and late mortality among patients with antecedent stroke subjected to cardiac surgical interventions with extracorporeal support. : A single-center retrospective study was conducted on 10,685 patients who underwent cardiac surgery with extracorporeal circulation at the Department of Cardiac Surgery. The first group comprised all patients eligible for cardiac surgery with extracorporeal circulation. The second group consisted of patients with a preoperative history of stroke. : In the study, a statistically significant association was observed between preoperative stroke and the occurrence of postoperative pneumonia (OR = 1.482, = 0.006), respiratory failure (OR = 1.497, = 0.006), renal failure (OR = 1.391, = 0.019), 30-day mortality (OR = 1.528, = 0.026), 90-day mortality (OR = 1.658, < 0.001), and one-year mortality (OR = 1.706, < 0.001). : Patients with a history of preoperative stroke more frequently experienced renal failure and respiratory-system complications such as pneumonia and respiratory failure. The survival time of patients with a history of preoperative stroke was shorter compared to that of the control group during the analyzed 30-day, 90-day, and one-year observation periods.

摘要

本研究旨在分析接受体外循环心脏手术干预的既往有中风病史患者的并发症风险,包括神经后遗症,以及早期和晚期死亡率。

在心脏外科进行了一项单中心回顾性研究,研究对象为10685例接受体外循环心脏手术的患者。第一组包括所有符合体外循环心脏手术条件的患者。第二组由术前有中风病史的患者组成。

在该研究中,观察到术前中风与术后肺炎(OR = 1.482,P = 0.006)、呼吸衰竭(OR = 1.497,P = 0.006)、肾衰竭(OR = 1.391,P = 0.019)、30天死亡率(OR = 1.528,P = 0.026)、90天死亡率(OR = 1.658,P < 0.001)和一年死亡率(OR = 1.706,P < 0.001)之间存在统计学上的显著关联。

术前有中风病史的患者更常出现肾衰竭以及呼吸系统并发症,如肺炎和呼吸衰竭。在分析的30天、90天和一年观察期内,术前有中风病史的患者的生存时间比对照组短。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9515/11277661/aa448b64ea7f/jcm-13-04045-g001.jpg

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