Dietel M, Arps H
Onkologie. 1985 Oct;8(5):278-80, 285. doi: 10.1159/000215676.
Antigens A, B, Lea, Leb, CA 12-5, CA 19-9 and CEA were prepared immunohistologically, a DNA-cytophotometry was carried out and the value of a new in vitro proliferation assay to test cytostatic drugs investigated. Material was as follows: 20 normal ovaries and 105 ovarian tumors. Blood group antigens were expressed at a high percentage from well-differentiated epithelial cells, CEA in 50% and CA 12-5 in 70% of the ovarian carcinoma. Predictions about the dignity of borderline tumors can be made with DNA-cytophotometry. The efficacy of 6 different cytostatic agents was investigated in a new in vitro proliferation assay.
通过免疫组织学方法制备了抗原A、B、Lea、Leb、CA 12 - 5、CA 19 - 9和癌胚抗原（CEA），进行了DNA细胞光度测定，并研究了一种用于测试细胞抑制药物的新型体外增殖试验的价值。材料如下：20个正常卵巢和105个卵巢肿瘤。血型抗原在高分化上皮细胞中高比例表达，50%的卵巢癌表达CEA，70%表达CA 12 - 5。通过DNA细胞光度测定可对交界性肿瘤的性质进行预测。在一种新型体外增殖试验中研究了6种不同细胞抑制药物的疗效。
