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新冠疫情期间疫苗接种覆盖率和发病率差异的综合监测:瑞典东南部的一项队列研究

Integrated Surveillance of Disparities in Vaccination Coverage and Morbidity during the COVID-19 Pandemic: A Cohort Study in Southeast Sweden.

作者信息

Spreco Armin, Dahlström Örjan, Nordvall Dennis, Fagerström Cecilia, Blomqvist Eva, Gustafsson Fredrik, Andersson Christer, Sjödahl Rune, Eriksson Olle, Hinkula Jorma, Schön Thomas, Timpka Toomas

机构信息

Department of Health, Medicine, and Caring Sciences, Linköping University, 58183 Linköping, Sweden.

Regional Executive Office, Region Östergötland, 58225 Linköping, Sweden.

出版信息

Vaccines (Basel). 2024 Jul 12;12(7):763. doi: 10.3390/vaccines12070763.

Abstract

We aimed to use the digital platform maintained by the local health service providers in Southeast Sweden for integrated monitoring of disparities in vaccination and morbidity during the COVID-19 pandemic. The monitoring was performed in the adult population of two counties ( = 657,926) between 1 February 2020 and 15 February 2022. The disparities monitored were relocated (internationally displaced), substance users, and suffering from a psychotic disorder. The outcomes monitored were COVID-19 vaccination, SARS-CoV-2 test results, and hospitalization with COVID-19. Relocated residents displayed an increased likelihood of remaining unvaccinated and a decreased likelihood of testing as well as increased risks of primary SARS-CoV-2 infection and hospitalization compared with the general population. Suffering from a major psychiatric disease was associated with an increased risk of remaining unvaccinated and an increased risk of hospitalization but a decreased risk of SARS-CoV-2 infection. From the digital monitoring, we concluded that the relocated minority received insufficient protection during the pandemic, suggesting the necessity for comprehensive promotion of overall social integration. Persons with major psychiatric diseases underused vaccination, while they benefitted from proactively provided testing, implying a need for active encouragement of vaccination. Further research is warranted on legal and ethical frameworks for digital monitoring in vaccination programs.

摘要

我们旨在利用瑞典东南部当地医疗服务提供商维护的数字平台,对新冠疫情期间疫苗接种和发病情况的差异进行综合监测。监测在2020年2月1日至2022年2月15日期间对两个县的成年人口(n = 657,926)进行。监测的差异人群为重新安置者(国际流离失所者)、药物使用者和患有精神疾病的人。监测的结果为新冠疫苗接种情况、SARS-CoV-2检测结果以及因新冠住院情况。与普通人群相比,重新安置的居民未接种疫苗的可能性增加,检测的可能性降低,原发性SARS-CoV-2感染和住院的风险增加。患有严重精神疾病与未接种疫苗的风险增加以及住院风险增加相关,但SARS-CoV-2感染风险降低。通过数字监测,我们得出结论,重新安置的少数群体在疫情期间未得到充分保护,这表明有必要全面促进整体社会融合。患有严重精神疾病的人疫苗接种不足,而他们从主动提供的检测中受益,这意味着需要积极鼓励接种疫苗。关于疫苗接种计划中数字监测的法律和伦理框架,有必要进行进一步研究。

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