艾滋病毒感染者中疫苗可预防疾病的负担
Burden of Vaccine-Preventable Diseases in People Living with HIV.
作者信息
Samaha Hady, Yigitkanli Arda, Naji Amal, Kazzi Bahaa, Tanios Ralph, Dib Serena Maria, Ofotokun Ighovwerha, Rouphael Nadine
机构信息
The Hope Clinic of the Emory Vaccine Center, Division of Infectious Diseases, Department of Medicine, Emory University, Decatur, GA 30030, USA.
Division of Infectious Diseases, Department of Medicine, Emory University, Atlanta, GA 30322, USA.
出版信息
Vaccines (Basel). 2024 Jul 16;12(7):780. doi: 10.3390/vaccines12070780.
Vaccine-preventable diseases (VPDs) pose a serious public health concern for people living with HIV (PLH). PLH experience a delayed and weakened response to many vaccines available, compared to the general population. Lower seroconversion rates, along with a decreased efficacy and durability of vaccines, increases the susceptibility of PLH to VPDs. Vaccination guidelines specifically targeting this population have been modified to overcome these challenges. However, vaccine uptake remains suboptimal due to multiple barriers, highlighting the need for further studies and the additional implementation of public health measures specifically tailored to PLH.
疫苗可预防疾病（VPDs）对艾滋病毒感染者（PLH）构成了严重的公共卫生问题。与普通人群相比，PLH对许多现有疫苗的反应延迟且减弱。较低的血清转化率，以及疫苗效力和持久性的降低，增加了PLH对VPDs的易感性。专门针对这一人群的疫苗接种指南已经过修改，以克服这些挑战。然而，由于多种障碍，疫苗接种率仍然不理想，这突出表明需要进一步研究，并额外实施专门为PLH量身定制的公共卫生措施。
Zotero 插件