手部闭合性骨折手术中的抗生素预防。
Antibiotic prophylaxis in surgery for closed fracture of the hand.
机构信息
Department of Hand and Upper Limb Surgery, Diseases of the Musculoskeletal System Division, Turku University Hospital, University of Turku and CoE TYKS ORTO, Turku, Finland.
Department of Orthopaedics and Traumatology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland; Department of Paediatric Surgery, Orthopaedics and Traumatology, University of Turku and Turku University Hospital, Turku, Finland.
出版信息
Hand Surg Rehabil. 2024 Sep;43(4):101753. doi: 10.1016/j.hansur.2024.101753. Epub 2024 Jul 26.
PURPOSE
Preoperative antibiotic prophylaxis is associated to internal fixation for closed phalangeal and metacarpal fracture, but its effectiveness is not known.
METHODS
In a consecutive series of 119 adult patients undergoing Kirschner-wire fixation for phalangeal or metacarpal fracture, 56.3% (n = 67) received antibiotic prophylaxis and 43.7% (n = 52) did not.
RESULTS
The rate of deep surgical site infection was 1.5% (n = 1) in the group with antibiotic prophylaxis and 1.9% (n = 1) in the group without. Minor skin irritation or infection of the pin tract occurred in 13.4% of cases (n = 9) in the group with antibiotic prophylaxis and 9.6% (n = 5) in the group without.
CONCLUSION
Our findings suggest that use of antibiotic prophylaxis could be reduced in the treatment of closed fractures of the hand treated with removable pins.
TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic IV (retrospective review).
目的
对于闭合性指/掌骨骨折的内固定，术前预防性应用抗生素是可行的，但对于其疗效尚不清楚。
方法
在一项连续的 119 例接受克氏针固定的成人掌指骨骨折患者中，56.3%（n=67）接受了抗生素预防治疗，43.7%（n=52）未接受。
结果
在接受抗生素预防治疗的组中，深部手术部位感染的发生率为 1.5%（n=1），而在未接受抗生素预防治疗的组中为 1.9%（n=1）。在接受抗生素预防治疗的组中，有 13.4%（n=9）发生轻微皮肤刺激或针道感染，而在未接受抗生素预防治疗的组中为 9.6%（n=5）。
结论
我们的研究结果表明，在手部闭合性骨折采用可移除克氏针治疗时，抗生素预防治疗的应用可以减少。
研究类型/证据水平：治疗性 IV（回顾性研究）。
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