Section on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.
Mathematics Department, Howard University, Washington, DC, United States.
Diabetes Res Clin Pract. 2024 Aug;214:111792. doi: 10.1016/j.diabres.2024.111792. Epub 2024 Jul 26.
Diagnosing diabetes by shortening the OGTT to 1-h and substituting 1-h post-load glucose (PG) ≥ 209 mg/dL for 2-h PG≥200 mg/dL has been proposed. One-hour PG≥209 mg/dL is from a meta-analysis without any African-descent populations. Our data suggest 1-h PG≥183 mg/dL maybe more optimal for Africans. As with waist circumference guidelines, population-specific thresholds may be appropriate.
通过将 OGTT 缩短至 1 小时并将 1 小时餐后血糖(PG)≥209mg/dL 替代 2 小时 PG≥200mg/dL 来诊断糖尿病的方法已经被提出。1 小时 PG≥209mg/dL 来自一项没有任何非裔人群的荟萃分析。我们的数据表明,1 小时 PG≥183mg/dL 可能对非洲人更优。就像腰围指南一样,特定人群的阈值可能是合适的。