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本文引用的文献

1
International Diabetes Federation Position Statement on the 1-hour post-load plasma glucose for the diagnosis of intermediate hyperglycaemia and type 2 diabetes.国际糖尿病联合会关于 1 小时负荷后血浆葡萄糖诊断中间高血糖和 2 型糖尿病的立场声明。
Diabetes Res Clin Pract. 2024 Mar;209:111589. doi: 10.1016/j.diabres.2024.111589. Epub 2024 Mar 7.
2
Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c.基于空腹血糖和糖化血红蛋白的全球糖尿病诊断和流行情况的变化。
Nat Med. 2023 Nov;29(11):2885-2901. doi: 10.1038/s41591-023-02610-2. Epub 2023 Nov 9.
3
A Scoping Review of Trials Designed to Achieve Remission of Type 2 Diabetes with Lifestyle Intervention Alone: Implications for Sub-Saharan Africa.仅通过生活方式干预实现2型糖尿病缓解的试验的范围综述:对撒哈拉以南非洲的启示
Diabetes Metab Syndr Obes. 2023 Mar 9;16:677-692. doi: 10.2147/DMSO.S403054. eCollection 2023.
4
Understanding the pathogenesis of lean non-autoimmune diabetes in an African population with newly diagnosed diabetes.了解新诊断糖尿病的非洲人群中非自身免疫性消瘦型糖尿病的发病机制。
Diabetologia. 2022 Apr;65(4):675-683. doi: 10.1007/s00125-021-05644-8. Epub 2022 Feb 9.
5
The diagnostic accuracy of HbA , compared to the oral glucose tolerance test, for screening for type 2 diabetes mellitus in Africa-A systematic review and meta-analysis.与口服葡萄糖耐量试验相比,血红蛋白A1c在非洲筛查2型糖尿病中的诊断准确性:一项系统评价和荟萃分析
Diabet Med. 2022 Apr;39(4):e14754. doi: 10.1111/dme.14754. Epub 2021 Dec 8.
6
Beta-cell failure rather than insulin resistance is the major cause of abnormal glucose tolerance in Africans: insight from the Africans in America study.β细胞衰竭而非胰岛素抵抗是导致非裔美国人糖代谢异常的主要原因:来自美国非洲裔人群研究的启示。
BMJ Open Diabetes Res Care. 2021 Sep;9(1). doi: 10.1136/bmjdrc-2021-002447.
7
Ethnic differences in beta cell function occur independently of insulin sensitivity and pancreatic fat in black and white men.黑人和白人男性的胰岛β细胞功能的种族差异独立于胰岛素敏感性和胰腺脂肪。
BMJ Open Diabetes Res Care. 2021 Mar;9(1). doi: 10.1136/bmjdrc-2020-002034.
8
Accuracy of 1-Hour Plasma Glucose During the Oral Glucose Tolerance Test in Diagnosis of Type 2 Diabetes in Adults: A Meta-analysis.口服葡萄糖耐量试验中 1 小时血浆葡萄糖诊断成年人 2 型糖尿病的准确性:一项荟萃分析。
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9
The OGTT is highly reproducible in Africans for the diagnosis of diabetes: Implications for treatment and protocol design.OGTT 在非洲人中对于糖尿病的诊断具有高度可重复性:对治疗和方案设计的影响。
Diabetes Res Clin Pract. 2020 Dec;170:108523. doi: 10.1016/j.diabres.2020.108523. Epub 2020 Oct 22.
10
Metabolic characteristics of Africans with normal glucose tolerance and elevated 1-hour glucose: insight from the Africans in America study.非洲裔美国人中糖耐量正常伴 1 小时血糖升高者的代谢特征:来自非洲裔美国人研究的观察。
BMJ Open Diabetes Res Care. 2020 Jan;8(1). doi: 10.1136/bmjdrc-2019-000837.

确定 1 小时负荷后血糖可诊断非洲裔美国人的糖尿病:来自非洲裔美国人研究的见解。

Determining the 1-hour post-load glucose which identifies diabetes in Africans: Insight from the Africans in America study.

机构信息

Section on Ethnicity and Health, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, United States.

Mathematics Department, Howard University, Washington, DC, United States.

出版信息

Diabetes Res Clin Pract. 2024 Aug;214:111792. doi: 10.1016/j.diabres.2024.111792. Epub 2024 Jul 26.

DOI:10.1016/j.diabres.2024.111792
PMID:39069090
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11351477/
Abstract

Diagnosing diabetes by shortening the OGTT to 1-h and substituting 1-h post-load glucose (PG) ≥ 209 mg/dL for 2-h PG≥200 mg/dL has been proposed. One-hour PG≥209 mg/dL is from a meta-analysis without any African-descent populations. Our data suggest 1-h PG≥183 mg/dL maybe more optimal for Africans. As with waist circumference guidelines, population-specific thresholds may be appropriate.

摘要

通过将 OGTT 缩短至 1 小时并将 1 小时餐后血糖(PG)≥209mg/dL 替代 2 小时 PG≥200mg/dL 来诊断糖尿病的方法已经被提出。1 小时 PG≥209mg/dL 来自一项没有任何非裔人群的荟萃分析。我们的数据表明,1 小时 PG≥183mg/dL 可能对非洲人更优。就像腰围指南一样,特定人群的阈值可能是合适的。