Division of Cardiology, Department of Pediatrics, Vanderbilt University Medical Center, Monroe Carrell Jr Children's Hospital, Nashville, TN 37232-2578, USA.
Division of Pulmonary Medicine, Department of Pediatrics, Vanderbilt University Medical Center, Carrell Jr Children's Hospital, Nashville, TN 37232-2578, USA.
Clin Chest Med. 2024 Sep;45(3):685-693. doi: 10.1016/j.ccm.2024.04.001.
Pulmonary hypertension (PH) may manifest at any age, including during childhood. While pediatric PH frequently associates with early life alterations that cause occult or overt pulmonary vascular disease, all forms of PH seen in adults are also found in children, although with different degrees of prevalence according to PH subtype. PH-specific medications, rapid implementation of therapeutic advances, multidisciplinary teams for improved child and family support, and programs to facilitate successful transition to adult care have contributed to substantial improvement in survival to adulthood.
肺动脉高压(PH)可发生于任何年龄,包括儿童期。虽然儿科 PH 常与导致隐匿性或显性肺血管疾病的早期生命改变相关,但在成人中所见的所有 PH 形式也存在于儿童中,尽管根据 PH 亚型的不同,其流行程度也不同。PH 特异性药物、治疗进展的快速实施、多学科团队以改善儿童和家庭支持,以及促进成功过渡到成人护理的计划,都有助于显著提高成年期的生存率。