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炎症性肠病作为腰椎间盘切除术后并发症和翻修手术的危险因素。

Inflammatory Bowel Disease as a Risk Factor for Complications and Revisions Following Lumbar Discectomy.

作者信息

Zhang Yi, Chi Jialun, Manley Brock, Oh Eunha, Yang Hanzhi, Wang Jesse, Li Xudong

机构信息

Department of Spine Surgery, Spinal Deformity Center, The Second Xiangya Hospital of Central South University, Changsha, China.

Department of Orthopaedic Surgery, University of Virginia, Charlottesville, USA.

出版信息

Global Spine J. 2025 May;15(4):1932-1938. doi: 10.1177/21925682241270069. Epub 2024 Jul 28.

Abstract

Study DesignRetrospective cohort study.ObjectivesPatients with IBD are at an increased risk for postoperative complications following surgery. The goal of this study is to investigate if inflammatory bowel disease (IBD) is a risk factor for complications following lumbar discectomy.MethodsWe identified IBD patients who underwent lumbar discectomy for lumbar disc herniation (LDH) and matched to them with controls without IBD in a1:5 ratio. We excluded patients with a history of spinal injury, cancer, infection, trauma, or surgery to remove the digestive tract. We used multivariate logistic regression analyses to compare postoperative outcomes, including 90-day complications, 90-day emergency department visits, and 90-day readmissions. In addition, 2-year re-discectomy rates and a 3-year lumbar fusion rate were compared between the cohorts.ResultsAfter applying the study criteria, we identified 6134 IBD patients with LDH for further analysis. With the exception of dura tears, patients with IBD had significantly higher rates of medical complications, incision-related complications, ED visits, and readmission rates compared to patients without IBD, especially for the 2-year and 3-year rates of disc recurrence and revision surgery.ConclusionsPatients with IBD who underwent lumbar discectomy are at a significantly higher rate of complications. Therefore, spine surgeons and other health care providers should be aware of this higher risk associated with IBD patients and properly treat the patients' IBD before surgery to lower these risks.

摘要

研究设计

回顾性队列研究。

目的

炎症性肠病(IBD)患者术后并发症风险增加。本研究的目的是调查炎症性肠病是否为腰椎间盘切除术后并发症的危险因素。

方法

我们确定了因腰椎间盘突出症(LDH)接受腰椎间盘切除术的IBD患者,并按1:5的比例将其与无IBD的对照组进行匹配。我们排除了有脊柱损伤、癌症、感染、创伤或消化道切除术病史的患者。我们使用多因素逻辑回归分析比较术后结果,包括90天并发症、90天急诊科就诊和90天再入院情况。此外,还比较了两组之间的2年再次椎间盘切除率和3年腰椎融合率。

结果

应用研究标准后,我们确定了6134例因LDH接受治疗的IBD患者进行进一步分析。除硬脊膜撕裂外,IBD患者的医疗并发症、切口相关并发症、急诊科就诊率和再入院率均显著高于无IBD的患者,尤其是2年和3年的椎间盘复发率和翻修手术率。

结论

接受腰椎间盘切除术的IBD患者并发症发生率显著更高。因此,脊柱外科医生和其他医疗保健提供者应意识到IBD患者存在的较高风险,并在手术前妥善治疗患者的IBD以降低这些风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9c6/12035395/8303d6deeb3e/10.1177_21925682241270069-fig1.jpg

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