Kim Ji-Young, Ma I Zhen, Hong Ki Yong
Department of Plastic and Reconstructive Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Department of Plastic and Reconstructive Surgery, Hanyang University Medical Center, Seoul, Korea.
J Breast Cancer. 2024 Aug;27(4):248-259. doi: 10.4048/jbc.2024.0045. Epub 2024 Jul 29.
Surgical site infections (SSIs) remain a concern after implant-based breast reconstruction, despite preventive measures. These infections can have serious consequences. This study evaluated the correlation between drain tip culture results and SSIs in this patient population.
We analyzed data from patients who underwent implant-based breast reconstruction between July 2021 and May 2023. Drain tip cultures were collected, and any SSIs occurring within one month of surgery were documented. We then compared clinical data with the culture results.
A total of 263 drain tip cultures were included. Notably, none of the 61 patients who underwent tissue expander removal and implant insertion had positive cultures. However, among the 202 patients who received tissue expanders or direct-to-implant procedures, 11 (5.45%) had positive cultures, with a total of 12 SSIs identified. Importantly, five of the 11 culture-positive wounds developed SSIs. Multivariate analysis revealed a significant two-way association between infection and positive drain tip cultures. For specifically, drain tip cultures showed excellent predictive value: sensitivity (33.33%), specificity (100%), positive predictive value (100%), and negative predictive value (95.96%).
Drain tip cultures from immediate implant-based breast reconstructions significantly correlated with SSIs. Close monitoring is crucial, especially when is identified in the culture.
尽管采取了预防措施，但基于植入物的乳房重建术后手术部位感染（SSIs）仍然是一个令人担忧的问题。这些感染可能会产生严重后果。本研究评估了该患者群体中引流管尖端培养结果与手术部位感染之间的相关性。
我们分析了2021年7月至2023年5月期间接受基于植入物的乳房重建的患者的数据。收集了引流管尖端培养物，并记录了手术一个月内发生的任何手术部位感染。然后我们将临床数据与培养结果进行了比较。
共纳入263份引流管尖端培养物。值得注意的是，61例接受组织扩张器取出和植入物植入的患者中，没有培养结果呈阳性的。然而，在202例接受组织扩张器或直接植入手术的患者中，11例（5.45%）培养结果呈阳性，共发现12例手术部位感染。重要的是，11例培养阳性的伤口中有5例发生了手术部位感染。多变量分析显示感染与引流管尖端培养阳性之间存在显著的双向关联。具体而言，引流管尖端培养显示出优异的预测价值：敏感性（33.33%）、特异性（100%）、阳性预测值（100%）和阴性预测值（95.96%）。
即刻基于植入物的乳房重建的引流管尖端培养结果与手术部位感染显著相关。密切监测至关重要，尤其是当培养中发现 时。 （最后一句原文似乎不完整）
