Neurology Service, University Hospital Marqués de Valdecilla-IDIVAL, Santander, Spain.
Universidad de Cantabria (UC), Spain.
Tremor Other Hyperkinet Mov (N Y). 2024 Jul 22;14:38. doi: 10.5334/tohm.910. eCollection 2024.
Severe hypomagnesemia is an increasingly recognized cause of acute and reversible cerebellar ataxia, often accompanied by cerebellar oculomotor signs such as jerky horizontal or downbeat nystagmus and very rarely ocular flutter.
This video illustrates horizontal pendular nystagmus in a patient with acute onset cerebellar ataxia associated with severe hypomagnesemia.
Acquired pendular nystagmus can be distinguished from macrosaccadic oscillations and ocular flutter in that the former is composed of two slow phases of equal velocity and the latter of two fast phases of saccadic type with or without intersaccadic interval, respectively. It is most commonly associated with demyelinating, toxic, metabolic, and genetic disorders, but has not been reported in association with severe hypomagnesemia.
严重低镁血症是急性和可逆性小脑性共济失调的一个日益被认识的原因，常伴有小脑眼球运动体征，如阵发性水平或下跳性眼球震颤，非常罕见的眼球扑动。
本视频演示了一例急性起病小脑性共济失调伴严重低镁血症患者的水平摆动性眼球震颤。
获得性摆动性眼球震颤可与巨扫视性眼球震颤和眼球扑动相区别，前者由两个速度相等的慢相组成，后者由两个具有或不具有扫视性间隔的快相组成。它最常与脱髓鞘、中毒、代谢和遗传疾病有关，但尚未有报道与严重低镁血症有关。
