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蛛网膜下腔颅内碘油沉积

Subarachnoid Intra-cranial Lipiodol Deposits.

作者信息

Saliba Tom, Pather Sanjiva, Cappeliez Olivier

机构信息

Radiology, Hôpital de Braine-L'Alleud, Braine-L'Alleud, BEL.

出版信息

Cureus. 2024 Jun 27;16(6):e63265. doi: 10.7759/cureus.63265. eCollection 2024 Jun.

DOI:10.7759/cureus.63265
PMID:39070367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11282481/
Abstract

Lipiodol, an oil-based contrast medium first introduced in 1944, was commonly used for various radiological exams until the 1980s, when it was replaced by water-soluble contrast media due to complications such as arachnoiditis and chronic irritations. Due to its slow resorption rate, asymptomatic lipiodol deposits can occasionally be found incidentally. This case report describes a 93-year-old man who presented to the emergency department after a fall. A non-contrast head CT scan, performed to rule out subarachnoid hemorrhage, revealed numerous hyperdense droplets in the subarachnoid spaces of the brain, primarily around the temporal lobes. Further investigation uncovered a previous pelvic X-ray showing similar hyperdense droplets around the cauda equina. The patient's history indicated a lipiodol myelography performed 51 years earlier. Lipiodol deposits are generally found in the lumbar region, making an intra-cranial location particularly rare. When present, these deposits are visible as radiopaque droplets on X-rays, hyperdense droplets on CT scans, and hyper-T1 on MRI, though the T2 signal is variable. Though lipiodol deposits are generally left untreated, symptomatic spinal deposits may be surgically removed. This rare case underscores the importance of thorough patient history in diagnosing subarachnoid lipiodol deposits, a condition relevant only in older patients who underwent myelography before the 1980s.

摘要

碘油是一种油基造影剂,于1944年首次引入,直到20世纪80年代,它一直被广泛用于各种放射学检查,后来由于诸如蛛网膜炎和慢性刺激等并发症,被水溶性造影剂所取代。由于其吸收速度缓慢,偶尔会意外发现无症状的碘油沉积。本病例报告描述了一名93岁男性,在跌倒后被送往急诊科。为排除蛛网膜下腔出血而进行的非增强头部CT扫描显示,在脑蛛网膜下腔,主要是颞叶周围,有大量高密度液滴。进一步调查发现,之前的骨盆X光片显示马尾神经周围有类似的高密度液滴。患者病史显示51年前曾进行过碘油脊髓造影。碘油沉积通常见于腰椎区域,颅内出现极为罕见。当存在碘油沉积时,在X光片上可见为不透射线的液滴,在CT扫描上为高密度液滴,在MRI上为高T1信号,尽管T2信号有所不同。虽然碘油沉积一般无需治疗,但有症状的脊髓沉积可能需要手术切除。这个罕见病例强调了详细了解患者病史对于诊断蛛网膜下腔碘油沉积的重要性,这种情况仅与20世纪80年代以前接受过脊髓造影的老年患者有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e063/11282481/25a04b137d22/cureus-0016-00000063265-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e063/11282481/18186b0dab08/cureus-0016-00000063265-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e063/11282481/985be3d4ea6b/cureus-0016-00000063265-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e063/11282481/1055c58147c9/cureus-0016-00000063265-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e063/11282481/25a04b137d22/cureus-0016-00000063265-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e063/11282481/18186b0dab08/cureus-0016-00000063265-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e063/11282481/985be3d4ea6b/cureus-0016-00000063265-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e063/11282481/1055c58147c9/cureus-0016-00000063265-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e063/11282481/25a04b137d22/cureus-0016-00000063265-i04.jpg

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本文引用的文献

1
Intracranial iodinated contrast medium deposits 50 years following a previous myelography: A case report and literature review.既往脊髓造影术后50年的颅内碘化造影剂沉积:一例报告及文献综述
Radiol Case Rep. 2023 Jun 15;18(9):2876-2879. doi: 10.1016/j.radcr.2023.05.044. eCollection 2023 Sep.
2
Unusual radiographic images of radiopaque contrast media incidentally observed in intracranial region: two case reports.颅内区域偶然发现的不透射线造影剂的异常影像学表现:两例报告
Eur Oral Res. 2018 Sep;52(3):167-169. doi: 10.26650/eor.2018.532. Epub 2018 Sep 1.
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Magnetic resonance imaging findings of remnants of an intradural oil-based contrast agent: report of a case.
硬脊膜内油基造影剂残留的磁共振成像表现:一例报告
J Spinal Cord Med. 2012 May;35(3):187-90. doi: 10.1179/2045772312Y.0000000002. Epub 2012 Feb 4.
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Iodinated organic compounds as contrast media for radiographic diagnoses; escape of pantopaque from the intracranial subarachnoid space of dogs.碘化有机化合物作为放射诊断的造影剂;碘苯酯从犬颅内蛛网膜下腔的逸出。
Radiology. 1946 Jul;47:47-50. doi: 10.1148/47.1.47.
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Thoracic spinal iophendylate-induced arachnoiditis mimicking an intramedullary spinal cord neoplasm. Case report.胸部脊髓碘苯酯诱发的蛛网膜炎酷似脊髓髓内肿瘤。病例报告。
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