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Spontaneous NETosis and type I IFN signaling activation in resting neutrophils of chronic granulomatous disease patients with mutations.

作者信息

Lu Zhengjing, Mou Wenjun, He Jianxin, Ge Xuedong, Wang Xiaolin, Gui Jingang

机构信息

Laboratory of Tumor Immunology, Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.

Department of Respiratory Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, China National Clinical Research Center for Respiratory Diseases, Beijing 100045, China.

出版信息

Genes Dis. 2023 Sep 20;11(6):101118. doi: 10.1016/j.gendis.2023.101118. eCollection 2024 Nov.

DOI:10.1016/j.gendis.2023.101118
PMID:39070548
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11278796/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da2/11278796/b51754c20062/figs2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da2/11278796/8e547249d817/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da2/11278796/e37e7c8bc310/figs1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da2/11278796/b51754c20062/figs2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da2/11278796/8e547249d817/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da2/11278796/e37e7c8bc310/figs1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4da2/11278796/b51754c20062/figs2.jpg

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本文引用的文献

1
Detrimental Effect of Type I IFNs During Acute Lung Infection With Is Mediated Through the Stimulation of Neutrophil NETosis.Ⅰ型干扰素在急性肺感染中的有害作用是通过刺激中性粒细胞 NETosis 介导的。
Front Immunol. 2019 Sep 11;10:2190. doi: 10.3389/fimmu.2019.02190. eCollection 2019.
2
Neutrophil extracellular traps (NETs) in autoimmune diseases: A comprehensive review.中性粒细胞胞外陷阱（NETs）在自身免疫性疾病中的作用：全面综述。
Autoimmun Rev. 2017 Nov;16(11):1160-1173. doi: 10.1016/j.autrev.2017.09.012. Epub 2017 Sep 9.
3
Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.
富含氧化线粒体DNA的中性粒细胞胞外陷阱具有干扰性，并导致狼疮样疾病。
Nat Med. 2016 Feb;22(2):146-53. doi: 10.1038/nm.4027. Epub 2016 Jan 18.
4
Reactive oxygen species deficiency induces autoimmunity with type 1 interferon signature.活性氧缺乏会诱导具有1型干扰素特征的自身免疫。
Antioxid Redox Signal. 2014 Dec 1;21(16):2231-45. doi: 10.1089/ars.2013.5828. Epub 2014 Jul 29.
5
X-CGDbase: a database of X-CGD-causing mutations.X-CGDbase：一个由导致X连锁慢性肉芽肿病（X-CGD）的突变组成的数据库。
Immunol Today. 1996 Nov;17(11):517-21. doi: 10.1016/0167-5699(96)30060-1.