Hattab Rashid M, Jarrar Zeid, Al Sharie Sarah, Al-Hussaini Maysa, Obeidat Mouness
Jordanian Royal Medical Services, Amman, Jordan.
Faculty of Medicine, University of Jordan, Amman, Jordan.
Rare Tumors. 2024 Jul 25;16:20363613241267740. doi: 10.1177/20363613241267740. eCollection 2024.
Intraventricular schwannomas are extremely rare, typically benign tumors originating from Schwann cells, which are not normally found within the ventricular system. Their presence challenges conventional understanding of tumor origins and complicates diagnosis and management. We report the case of a 19-year-old female presenting with a drop attack and headache, with no significant medical history. MRI revealed a heterogeneously enhancing lesion in the right lateral ventricle. Differential diagnoses included malignant tumors; however, histopathological examination post-surgical resection confirmed an intraventricular schwannoma. Postoperative outcomes were favorable, with successful CSF diversion via a right occipital ventriculoperitoneal shunt for isolated right temporal hydrocephalus. This case is notable for its atypical presentation in a young patient, challenging the conventional understanding that intraventricular schwannomas primarily affect older individuals. In addition, the correct diagnosis and successful management of a rare intraventricular schwannoma underscores the importance of considering this rare diagnosis in patients with nonspecific neurological symptoms and intraventricular lesions. This case, alongside the literature review, enriches the body of evidence on intraventricular schwannomas, highlighting the critical role of surgical intervention and the need for a comprehensive diagnostic approach.
脑室内神经鞘瘤极为罕见,通常是起源于雪旺细胞的良性肿瘤,而雪旺细胞在脑室系统中通常并不存在。它们的出现挑战了对肿瘤起源的传统认识,并使诊断和治疗复杂化。我们报告了一例19岁女性病例,该患者出现跌倒发作和头痛,无明显病史。磁共振成像(MRI)显示右侧脑室内有一个不均匀强化的病灶。鉴别诊断包括恶性肿瘤;然而,手术切除后的组织病理学检查证实为脑室内神经鞘瘤。术后结果良好,通过右侧枕部脑室腹腔分流术成功实现脑脊液引流,治疗孤立性右侧颞叶脑积水。该病例在年轻患者中的非典型表现值得关注,挑战了脑室内神经鞘瘤主要影响老年人的传统认识。此外,对罕见的脑室内神经鞘瘤的正确诊断和成功治疗强调了在有非特异性神经症状和脑室内病变的患者中考虑这种罕见诊断的重要性。该病例以及文献综述丰富了关于脑室内神经鞘瘤的证据体系,突出了手术干预的关键作用以及全面诊断方法的必要性。