Blangis Flora, Drouin Jérôme, Launay Elise, Miranda Sara, Zureik Mahmoud, Cohen Jérémie F, Weill Alain, Dray-Spira Rosemary, Chalumeau Martin
EPI-PHARE Scientific Interest Group, French National Agency for Medicines and Health Products Safety (ANSM), French National Health Insurance (CNAM), F-93200, Saint-Denis, France.
Obstetrical, Perinatal and Pediatric Epidemiology Research Team, Centre of Research in Epidemiology and StatisticS, Université Paris Cité, INSERM, F-75014, Paris, France.
Lancet Reg Health Eur. 2024 May 14;42:100921. doi: 10.1016/j.lanepe.2024.100921. eCollection 2024 Jul.
Identifying risk factors for early child physical abuse (CPA) is crucial for understanding its mechanisms and defining effective preventive interventions. We aimed to identify maternal, prenatal and postnatal factors associated with early CPA.
This cohort study was based on comprehensive data from the Mother-Child EPI-MERES nationwide register and included all infants born alive in France between 2010 and 2019. Factors associated with early CPA (before age 1) were identified with a multilevel Cox regression model with random intercepts at the regional level.
Among the 6,897,384 included infants, 2994 (40/100,000) had a diagnosis of early CPA, at a median age of 4 months. Independent factors most strongly associated with early CPA were maternal low financial resources (adjusted hazard ratio [aHR] 1.91; 95% confidence interval [95% CI] 1.67-2.18), maternal age <20 years versus 35-40 years (aHR 7.06; 95% CI 6.00-8.31), maternal alcohol use disorder (aHR 1.85; 95% CI 1.48-2.31), opioid use disorder (aHR 1.90; 95% CI 1.41-2.56), intimate partner violence (aHR 3.33; 95% CI 2.76-4.01), diagnosis of a chronic mental disorder (aHR 1.50; 95% CI 1.14-1.97) or somatic disorder (aHR 1.55; 95% CI 1.32-1.83), hospitalisation for a mental disorder (aHR 1.88; 95% CI 1.49-2.36), very preterm birth (aHR 2.15; 95% CI 1.68-2.75), and diagnosis of a chronic severe neurocognitive disorder in the infant (aHR 14.37; 95% CI 11.85-17.44).
Independent risk factors of early CPA identified at the national level in France may help in understanding CPA mechanisms and developing effective prevention programs including risk-stratification tools to optimise the allocation of parenting interventions to parents who could most benefit from them.
Ile-de-France regional council, L'Oréal-UNESCO For Women In Science France Young Talent Award, French National Observatory for Child Protection [ONPE], French Association of Ambulatory Paediatrics [AFPA], HUGO university hospitals network, Mustela Foundation and Sauver la Vie prizes.
识别幼儿期身体虐待(CPA)的风险因素对于理解其机制和确定有效的预防干预措施至关重要。我们旨在确定与早期CPA相关的母亲、产前和产后因素。
这项队列研究基于全国母婴EPI-MERES登记处的综合数据,纳入了2010年至2019年在法国出生的所有活产婴儿。通过在地区层面具有随机截距的多水平Cox回归模型,确定与早期CPA(1岁之前)相关的因素。
在纳入的6,897,384名婴儿中,2994名(40/100,000)被诊断为早期CPA,中位年龄为4个月。与早期CPA最密切相关的独立因素包括母亲经济资源匮乏(调整后风险比[aHR] 1.91;95%置信区间[95%CI] 1.67 - 2.18)、母亲年龄<20岁与35 - 40岁相比(aHR 7.06;95%CI 6.00 - 8.31)、母亲酒精使用障碍(aHR 1.85;95%CI 1.48 - 2.31)、阿片类药物使用障碍(aHR 1.90;95%CI 1.41 - 2.56)、亲密伴侣暴力(aHR 3.33;95%CI 2.76 - 4.01)、慢性精神障碍诊断(aHR 1.50;95%CI 1.14 - 1.97)或躯体疾病诊断(aHR 1.55;95%CI 1.32 - 1.83)、因精神障碍住院(aHR 1.88;95%CI 1.49 - 2.36)、极早产(aHR 2.15;95%CI 1.68 - 2.75)以及婴儿慢性严重神经认知障碍诊断(aHR 14.37;95%CI 11.85 - 17.44)。
在法国全国层面确定的早期CPA独立风险因素可能有助于理解CPA机制,并制定有效的预防计划,包括风险分层工具,以优化将育儿干预措施分配给最能从中受益的父母。
法兰西岛大区议会、欧莱雅 - 联合国教科文组织法国女科学家青年人才奖、法国国家儿童保护观察站[ONPE]、法国门诊儿科学会[AFPA]、雨果大学医院网络、妙思乐基金会和拯救生命奖。