Dolz M, Drakopoulos A, Aurich B, Frentzel-Beyme B
Z Urol Nephrol. 1985 Sep;78(9):465-74.
Thirty-five cases of prostate carcinoma were followed after orchiectomy and during drug therapy using both ultrasound and digital palpation to measure the prostate. Following orchiectomy and drug therapy the prostate shrunk an average of one third within six months independent of the grading and staging of the carcinoma. The biggest shrinkage was observed in the first two months after therapy. There was agreement between transrectal ultrasonography (TPS) and digital palpation in judging the prostate capsule in two thirds of the cases. Ultrasonographically, a downstaging of the capsule in twenty per cent and an upstaging in fourteen per cent of the cases was found. Three quarters of the G II prostate carcinomas improved ultrasonographically in structure and capsule in the twelve month period of observation while two thirds of the G III prostate carcinomas did not improve. According to our results the routine use of TPS seems not to be indicated when only gross measurement is desired. However TPS is an objective and reliable method für testing the effects of medication on prostate carcinomas.
对35例前列腺癌患者在睾丸切除术后及药物治疗期间，采用超声和直肠指诊测量前列腺。睾丸切除术后及药物治疗后，无论癌症的分级和分期如何，前列腺在6个月内平均缩小了三分之一。最大的缩小发生在治疗后的前两个月。经直肠超声检查（TPS）和直肠指诊在三分之二的病例中对前列腺包膜的判断结果一致。超声检查发现，20%的病例包膜分期降低，14%的病例包膜分期升高。在12个月的观察期内，四分之三的G II期前列腺癌在结构和包膜方面超声表现有所改善，而三分之二的G III期前列腺癌没有改善。根据我们的结果，当只需要大致测量时，似乎不需要常规使用TPS。然而，TPS是一种客观可靠的方法，可用于测试药物对前列腺癌的疗效。
