Wan Dan-Dan, Li Xiao-Ju, Wang Xing-Ru, Liu Tian-Xi
School of Clinical Medicine, Qujing Medical College, Qujing 655000, Yunnan Province, China.
Department of Hepatobiliary Surgery, Qujing Second People's of Yunnan Province, Qujing 655000, Yunnan Province, China.
World J Gastrointest Oncol. 2024 Jul 15;16(7):3350-3356. doi: 10.4251/wjgo.v16.i7.3350.
The incidence of multiple primary carcinomas (MPC) varies greatly, ranging from 0.73% to 11.70% in foreign countries, with duo-duplex carcinoma being the most common, trio-duplex carcinoma and above being rare, and simultaneous multigenic carcinoma being even rarer, accounting for 18.4% to 25.3% of the incidence of MPC. However, there is no report regarding patients presenting with simultaneous dual-origin carcinoma of the liver and colon and heterochronous pancreatic cancer.
We report a special case of multifocal carcinoma, in which one patient had a medical condition of primary liver and colon cancer and pancreatic cystadenocarcinoma 2 years after surgery. Through aggressive advanced fluorescent laparoscopic techniques, standardized immunotherapy, targeting, and chemotherapy, a better prognosis and a desirable survival period were achieved for the patient.
There is a need to clarify the nature of MPC through advanced surgical means to ensure better diagnosis and treatment.
多原发性癌(MPC)的发病率差异很大,在国外为0.73%至11.70%,其中双发癌最为常见,三发及以上的双发癌罕见,同时性多原发癌更为罕见,占MPC发病率的18.4%至25.3%。然而,尚无关于同时发生肝和结肠双原发癌以及异时性胰腺癌患者的报道。
我们报告了一例多灶性癌的特殊病例,该患者在原发性肝癌和结肠癌手术后2年出现胰腺囊腺癌。通过积极采用先进的荧光腹腔镜技术、标准化免疫治疗、靶向治疗和化疗,患者获得了较好的预后和理想的生存期。
有必要通过先进的手术手段明确MPC的性质,以确保更好的诊断和治疗。