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异时性多灶性癌：一例报告。

Metachronous multifocal carcinoma: A case report.

作者信息

Wan Dan-Dan, Li Xiao-Ju, Wang Xing-Ru, Liu Tian-Xi

机构信息

School of Clinical Medicine, Qujing Medical College, Qujing 655000, Yunnan Province, China.

Department of Hepatobiliary Surgery, Qujing Second People's of Yunnan Province, Qujing 655000, Yunnan Province, China.

出版信息

World J Gastrointest Oncol. 2024 Jul 15;16(7):3350-3356. doi: 10.4251/wjgo.v16.i7.3350.

DOI:10.4251/wjgo.v16.i7.3350
PMID:39072183
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11271799/
Abstract

BACKGROUND

The incidence of multiple primary carcinomas (MPC) varies greatly, ranging from 0.73% to 11.70% in foreign countries, with duo-duplex carcinoma being the most common, trio-duplex carcinoma and above being rare, and simultaneous multigenic carcinoma being even rarer, accounting for 18.4% to 25.3% of the incidence of MPC. However, there is no report regarding patients presenting with simultaneous dual-origin carcinoma of the liver and colon and heterochronous pancreatic cancer.

CASE SUMMARY

We report a special case of multifocal carcinoma, in which one patient had a medical condition of primary liver and colon cancer and pancreatic cystadenocarcinoma 2 years after surgery. Through aggressive advanced fluorescent laparoscopic techniques, standardized immunotherapy, targeting, and chemotherapy, a better prognosis and a desirable survival period were achieved for the patient.

CONCLUSION

There is a need to clarify the nature of MPC through advanced surgical means to ensure better diagnosis and treatment.

摘要

背景

多原发性癌（MPC）的发病率差异很大，在国外为0.73%至11.70%，其中双发癌最为常见，三发及以上的双发癌罕见，同时性多原发癌更为罕见，占MPC发病率的18.4%至25.3%。然而，尚无关于同时发生肝和结肠双原发癌以及异时性胰腺癌患者的报道。

病例摘要

我们报告了一例多灶性癌的特殊病例，该患者在原发性肝癌和结肠癌手术后2年出现胰腺囊腺癌。通过积极采用先进的荧光腹腔镜技术、标准化免疫治疗、靶向治疗和化疗，患者获得了较好的预后和理想的生存期。

结论

有必要通过先进的手术手段明确MPC的性质，以确保更好的诊断和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/0fccc2da86d3/WJGO-16-3350-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/52f58e0f76dd/WJGO-16-3350-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/05d97a9bb11c/WJGO-16-3350-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/5abd5ee614d6/WJGO-16-3350-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/8997bd7fc86f/WJGO-16-3350-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/d59925da655c/WJGO-16-3350-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/fdd2a8266496/WJGO-16-3350-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/0fccc2da86d3/WJGO-16-3350-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/52f58e0f76dd/WJGO-16-3350-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/05d97a9bb11c/WJGO-16-3350-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/5abd5ee614d6/WJGO-16-3350-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/8997bd7fc86f/WJGO-16-3350-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/d59925da655c/WJGO-16-3350-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/fdd2a8266496/WJGO-16-3350-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a03/11271799/0fccc2da86d3/WJGO-16-3350-g007.jpg

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