School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China.
J Mater Chem B. 2024 Aug 28;12(34):8267-8284. doi: 10.1039/d4tb00779d.
Biodegradable metals, including magnesium, iron, and zinc alloys, have attracted extensive attention due to their good biodegradability and biocompatibility. However, the mechanical properties and corrosion rates of most biodegradable metallic materials have not yet reached the ideal level required for clinical applications. Strontium, as an element of Group IIA in the periodic table of elements, has similar chemical and biological properties to calcium. It can promote bone tissue development and increase bone strength. In addition, strontium can also promote angiogenesis and facilitate the repair of infarcted heart activity. Thus, strontium is commonly used as one of the most alloying elements to improve the and properties of biodegradable metals. Besides, strontium is also widely used in various bioactive coatings to improve the comprehensive properties of biodegradable metals. This paper outlines the role of strontium in the human body and summarizes recent research and applications of strontium-containing biodegradable metallic materials. Finally, this paper also provides an outlook on the challenges faced in applying and researching strontium in biodegradable metals.
可生物降解金属,包括镁、铁和锌合金,由于其良好的生物降解性和生物相容性而受到广泛关注。然而,大多数可生物降解金属材料的机械性能和腐蚀速率尚未达到临床应用所需的理想水平。锶是元素周期表第 IIA 族的一种元素,具有与钙相似的化学和生物学性质。它可以促进骨组织的发育并增加骨强度。此外,锶还可以促进血管生成并有助于修复梗死的心脏活动。因此,锶通常被用作改善可生物降解金属的 和 性能的最常用的合金元素之一。此外,锶还广泛用于各种生物活性涂层中,以提高可生物降解金属的综合性能。本文概述了锶在人体中的作用,并总结了含锶可生物降解金属材料的最新研究和应用。最后,本文还对可生物降解金属中锶的应用和研究面临的挑战进行了展望。