Newcastle University and Great North Children's Hospital, Newcastle upon Tyne, UK.
Clin Endocrinol (Oxf). 2024 Sep;101(3):223-233. doi: 10.1111/cen.15110. Epub 2024 Jul 29.
The spectrum of thyroid disorders presenting to paediatricians is different to that seen by adult physicians. Referrals reflect cases detected by the neonatal screening programme for congenital hypothyroidism and many of the inherited defects of thyroid hormone generation or action will be manifest in early life. Autoimmune thyroid disease can be particularly challenging to manage in the young and the potential impact of thyroid status on neurodevelopment and schooling are key considerations throughout childhood and adolescence.
儿科医生所面对的甲状腺疾病谱与成人医生不同。转诊反映了新生儿先天性甲状腺功能减退症筛查计划所发现的病例,许多甲状腺激素生成或作用的遗传性缺陷将在生命早期表现出来。自身免疫性甲状腺疾病在儿童期的管理尤其具有挑战性,甲状腺功能对神经发育和学业的潜在影响是整个儿童期和青春期的关键考虑因素。